Long-term outcomes comparison of immediate and delayed surgical intervention for penile fracture: A systematic review and meta-analysis

Yusuf, Muhlis; Yogiswara, Niwanda; Soebadi, Mohammad Ayodhia; Duarsa, Gede Wirya Kusuma; Wirjopranoto, S.

doi:10.1016/j.sexol.2022.07.001

Cited by 6 publications

(4 citation statements)

References 35 publications

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“…Alpha-1 adrenergic receptors are the most common adrenoceptors in the urinary tract, including the ureters. 16 In the ureters, alpha-1 adrenergic receptors are distributed more distally than in the middle and proximal portions, especially the α1D subtype. 17 Stimulation of α receptors increases the strength of ureteric contractions and the frequency of ureteral peristalsis.…”

Section: Discussionmentioning

confidence: 98%

“…3,5 Meanwhile, another research stated that administration of alpha-blockers takes at least 5 days to achieve a stable dose. 16 Tamsulosin, a highly selective 1d adrenoceptor antagonist, has been shown to boost stone ejection rates for distal ureteral calculi in several studies. 24 Side effects that arise as a result of the administration of tamsulosin in children can occur in the form of hypotension, asthenia, syncope, palpitations, somnolence, nausea, vomiting, headache, nasal congestion, and dizziness.…”

Section: Discussionmentioning

confidence: 99%

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The Efficacy of Preoperative Tamsulosin on Ureteroscopy Access in Pediatrics: A Systematic Review and Meta-Analysis

Singgih,

Oktaviani,

Pranowo Sampurno Secodiningrat

et al. 2023

Siriraj Med J

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Objective: The incidence of urolithiasis in pediatrics increases to 4-10% annually. One of the methods for treating urolithiasis is ureteroscopy (URS). The small anatomy in pediatrics often makes the initial URS unsuccessful. Alpha blockers, a drug that can relax the ureteral muscles, is a therapy that can be considered before URS is carried out. The objective of this study is to evaluate the efficacy of preoperative tamsulosin for URS access in pediatrics. Materials and Methods: We conducted a search using four databases, including PubMed, EBSCO, Cochrane Library, and ProQuest. This study includes randomized controlled trials (RCTs), retrospective and prospective studies, which compared the efficacy of preoperative alpha blockers and placebo or non-placebo controls in pediatrics undergoing ureteroscopy. The outcome of interest was the success rate of URS access and the duration of surgery. Results: A total of 120 studies were identified from a database search. There were 3 studies included in this review involving 235 patients. The meta-analysis was conducted using a random-effects model. The results of the meta-analysis showed that alpha blockers provided a successful rate of ureteroscopy access in pediatric patients (Odds ratio (OR) 2.73; 95% confidence interval (CI) 1.52 up to 4.91; p=0.0008). Duration of surgery did not show significant results (Mean difference (MD) 3.46; 95% CI -3.59 up to 10.50; p=0.34).

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

The Efficacy of Preoperative Tamsulosin on Ureteroscopy Access in Pediatrics: A Systematic Review and Meta-Analysis

Singgih,

Oktaviani,

Pranowo Sampurno Secodiningrat

et al. 2023

Siriraj Med J

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“…Prompt surgical exploration with the repair of the tunical tear with an absorbable or inverting non-absorbable suture is the standard of Care [13] The first surgical repair was published by Fetter and Gartmen in 1936 [14] Multiple published literature over the years has reiterated the fact that surgical management leads to near-total and prompt functional recovery. Similarly, there have been publications comparing non-conservative to conservative management.…”

Section: Discussionmentioning

confidence: 99%

Penile fracture : Our experience

Lanka,

Khan,

Madhu

et al. 2024

Sri Lanka j Surg

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Background: Penile fracture, though rare are more commonly seen in modern-day urological practice. It necessitates urgent and immediate surgical care. It can lead to severe mental and physical agony with functional limitations which could be either sexual or urinary or both. Precise and timely management combined with proper follow–up is mandatory. The emergency care surgeon/ Urologist should be abreast with the evaluation and prompt intervention can result in favourable outcomes.Materials and Methods: We performed a retrospective observational study at a tertiary care referral centre. The objective was to evaluate the causes, clinical presentation and outcome.Results: Nine (09) patients who reported at our centre were treated successfully and were later followed up for two years. The mean reporting time to the hospital was 40.8 hours (35 min-7 days) and all patients received prompt surgical management with 3 patients suffering minor complications at short-term follow-up. Vaginal intercourse was found to be the most common etiological cause for injury. Clinical evaluation and relevant history were sufficient to elucidate the diagnosis. No associated urethral injuries were presentConclusion: If typical symptoms are present (irrespective of signs) a diagnosis of penile fracture can be ascertained. Early exploration is preferable.

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“…Immediate surgical intervention, including hematoma evacuation and tunica albuginea repair, was initially recommended by Fernstrom [ 28 ]. Studies favoring surgery show shorter hospital stays, heightened patient satisfaction, and improved outcomes, including lower erectile dysfunction rates [ 29 ]. However, we could not assess the patient long term surgical outcomes as patient did not follow the follow-up plan.…”

Section: Discussionmentioning

confidence: 99%

Penile fracture: A case report

Imran,

Kamran,

Tanveer

et al. 2023

International Journal of Surgery Case Reports

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Long-term outcomes comparison of immediate and delayed surgical intervention for penile fracture: A systematic review and meta-analysis

Cited by 6 publications

References 35 publications

The Efficacy of Preoperative Tamsulosin on Ureteroscopy Access in Pediatrics: A Systematic Review and Meta-Analysis

The Efficacy of Preoperative Tamsulosin on Ureteroscopy Access in Pediatrics: A Systematic Review and Meta-Analysis

Penile fracture : Our experience

Penile fracture: A case report

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