2017
DOI: 10.1002/jhbp.465
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Long‐term outcomes and recurrence patterns of standard versus extended pancreatectomy for pancreatic head cancer: a multicenter prospective randomized controlled study

Abstract: Extended pancreatectomy does not have better short-term and long-term survival outcomes, and shows similar R0 rates and overall recurrence rates compared with standard pancreatectomy. Extended pancreatectomy does not have to be performed routinely for all cases of resectable pancreatic adenocarcinoma, especially considering its associated increased morbidity shown in our previous study.

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Cited by 40 publications
(36 citation statements)
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“…Recurrence after curative-intent surgery for PDAC is unfortunately a common feature and is encountered in more than 80% of patients (104)(105)(106). The recurrence can occur at the local site of resection and/or in the liver, peritoneum, lung or other distant sites.…”
Section: Resection For Recurrent Pdacmentioning
confidence: 99%
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“…Recurrence after curative-intent surgery for PDAC is unfortunately a common feature and is encountered in more than 80% of patients (104)(105)(106). The recurrence can occur at the local site of resection and/or in the liver, peritoneum, lung or other distant sites.…”
Section: Resection For Recurrent Pdacmentioning
confidence: 99%
“…The recurrence can occur at the local site of resection and/or in the liver, peritoneum, lung or other distant sites. A local recurrence is encountered in almost 75% of the patients after curative-intent surgery for PDAC, while distant metastases were observed in 66%-83% of the patients (mainly liver and peritoneal) (76,104,105).…”
Section: Resection For Recurrent Pdacmentioning
confidence: 99%
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“…However, subsequent studies have found that EPD does not result in survival bene ts and might increase the incidence of postoperative complications. [5][6][7][8][9][10] In 2014, the International Pancreatic Surgery Research Group (ISGPS) reached a consensus about SPD that includes the 5, 6, 8a, 12b1, 12b2, 12c, 13a, 13b, 14a, 14b, 17a, and 17b lymph nodes. [11] Furthermore, some researchers reported that lymphadenectomy that includes the 12b,12c, 13, and 17 lymph nodes can be performed safely and e ciently, without negatively affecting oncologic e cacy or long-term survival, only compared with EPD.…”
Section: Introductionmentioning
confidence: 99%
“…Во многом неудовлетворительные результаты хирургического лечения протоковой аденокарциномы поджелудочной железы определяются высокой частотой местных рецидивов -локальных, перитонеальных и в оставшейся части паренхимы. По данным большинства исследователей [3], частота рецидивов достаточно стабильна и находится в пределах 30-47,6%. К факторам риска ранних (в течение года) перитонеальных рецидивов относят резекцию портомезентериального венозного сегмента, длительность операции (648 мин и более), большую кровопотерю (2179 мл и более), гемотрансфузию, размер опухоли, инвазию в воротную вену, артериальную инвазию и дифференцировку опухоли.…”
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