Long-term Outcomes After Percutaneous Radiofrequency Ablation for Renal Cell Carcinoma

Zagoria, Ronald J.; Pettus, Joseph A.; Rogers, Morgan; Werle, David M.; Childs, David D.; Leyendecker, John R.

doi:10.1016/j.urology.2010.12.077

Cited by 144 publications

(84 citation statements)

References 27 publications

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“…For adequate destruction of tumor tissue, the entire volume of an index tumor must be treated with temperatures that are above the threshold for cell death, typically 50-60°C [19]. RFA is a reliable and safe ablation technique that has been used successfully for years in the treatment of small renal cell cancer (RCC) [1,20]. Zagoria et al [20], with a study with follow-up data exceeding 5 years, strongly support the durable efficacy of RFA for treatment of RCC.…”

Section: Experimental Comparison To Other Thermal Ablative Techniquesmentioning

confidence: 99%

“…RFA is a reliable and safe ablation technique that has been used successfully for years in the treatment of small renal cell cancer (RCC) [1,20]. Zagoria et al [20], with a study with follow-up data exceeding 5 years, strongly support the durable efficacy of RFA for treatment of RCC. However, it has some drawbacks: size and sinus extension of the tumor to be treated can increase the risk of technical failure, difficulty to completely ablate irregular-shape tumors, major influence by heat sink effect by blood circulation, depends on tissue impedance [21].…”

Section: Experimental Comparison To Other Thermal Ablative Techniquesmentioning

confidence: 99%

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Microwave ablation of renal tumors: state of the art and development trends

et al. 2014

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In the last decades an increased incidence of new renal tumor cases has been for clinically localized, small tumors \2.0 cm. This trend for small, low-stage tumors is the reflection of earlier diagnosis primarily as a result of the widespread and increasing use of non-invasive abdominal imaging modalities such as ultrasound, computerized tomography, and magnetic resonance imaging. Renal tumors are often diagnosed in elderly patients, with medical comorbidities whom the risk of surgical complications may pose a greater risk of death than that due to the tumor itself. In these patients, unsuitable for surgical approach, thermal ablation represents a valid alternative to traditional surgery. Thermal ablation is a less invasive, less morbid treatment option thanks to reduced blood loss, lower incidence of complications during the procedure and a less long convalescence. At present, the most widely used thermal ablative techniques are cryoablation, radiofrequency ablation and microwave ablation (MWA). MWA offers many benefits of other ablation techniques and offers several other advantages: higher intratumoral temperatures, larger tumor ablation volumes, faster ablation times, the ability to use multiple applicators simultaneously, optimal heating of cystic masses and tumors close to the vessels and less procedural pain. This review aims to provide the reader with an overview about the state of the art of microwave ablation for renal tumors and to cast a glance on the new development trends of this technique.

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Section: Experimental Comparison To Other Thermal Ablative Techniquesmentioning

confidence: 99%

Section: Experimental Comparison To Other Thermal Ablative Techniquesmentioning

confidence: 99%

Microwave ablation of renal tumors: state of the art and development trends

et al. 2014

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“…of percutaneous, image-guided tumor ablation methods, and RF ablation has been the method of choice because of its availability, safety, efficacy, and cost. In the clinical setting, RF ablation has shown promise for treating solid tumors, particularly those involving the liver (6, 7), kidneys (8,9), lungs (10,11,4,5), and the musculoskeletal system (12, 13).…”

Section: Clinical Applicationsmentioning

confidence: 99%

“…Surgery is the method of choice for localized RCC; however, there are a significant number of patients who are not suitable for surgery because of comorbid illnesses. RF ablation is emerging as a safe and effective alternative for elderly patients with early-stage RCC who are not surgical candidates (8), and there is increasing evidence that it can be a curative treatment option for these patients, sparing them the risk of mortality and substantial morbidity associated with surgery (9). RF ablation seems to provide the lowest rate of renal impairment compared to extirpative treatment options (37), which is particularly important in patients with a solitary kidney.…”

Section: Rf Ablation In Kidney Tumorsmentioning

confidence: 99%

“…In most cases, percutaneous RF ablation can be performed in patients under conscious sedation, by using medications similar to those used with any other interventional radiology procedure. In the clinical arena, RF ablation has been used for the treatment of various neoplasms, including metastases from a variety of primary tumors (4,5), such as hepatocellular carcinoma (HCC) (6,7), renal cell carcinoma (RCC) (8,9), non-small cell lung cancer (NSCLC) (10,11), and osteoid osteoma (12,13). In this article we review RF ablation techniques and their clinical implications.…”

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confidence: 99%

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Radiofrequency ablation: technique and clinical applications

Tatlı

Tapan²,

Morrison³

et al. 2011

Diagn Interv Radiol

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Radiofrequency ablation is the most commonly used percutaneous ablation technique and well-documented in the literature on focal therapies. It has become the image-guided ablation method of choice because of its efficacy, safety, and ease of use. Radiofrequency ablation has shown promise in treating selected solid tumors, particularly those involving the liver, kidneys, lungs, and the musculoskeletal system. It is a minimally invasive technique often used in inoperable patients with other comorbidities. Radiofrequency ablation requires a minimal hospital stay or can be performed on an outpatient basis. The aim of this article is to review radiofrequency ablation techniques and their clinical applications.

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