Long-Term Outcome of Epiretinal Membrane Surgery in Young Children

Bonnin, Sophie; Metge, F.; Guez, A.; Edelson, C.; Dureau, P.; Caputo, G.

doi:10.1097/iae.0000000000000732

Cited by 12 publications

(8 citation statements)

References 10 publications

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“…However, during the follow-up, spontaneous relief of the traction caused by the ERM was observed, with improvement in VA. That suggests that early surgery in selected cases could be of benefit in terms of recovery of VA, which have been concluded in some other works [9, 11, 12]. …”

Section: Discussionsupporting

confidence: 63%

Combined Hamartoma of the Retina and Retinal Pigment Epithelium in a Patient with Gorlin Syndrome: Spontaneous Partial Resolution of Traction Caused by Epiretinal Membrane

Sánchez-Vicente

Contreras-Díaz

Rueda

et al. 2016

Case Reports in Ophthalmological Medicine

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Purpose. To describe the case of spontaneous resolution of epiretinal membrane in a patient with Combined Hamartoma of the Retina and Retinal Pigment Epithelium (CHR-RPE), in the clinical context of Gorlin Syndrome (GS). Methods. Observational case report of a 12-year-old female patient is presented. The diagnosis of CHRRPE was made by OCT and fundus examination, which showed a mound of disorganized tissue originating from retina and retinal pigment epithelium. Epiretinal membrane (EM) was also detected. Genetic study was performed to confirm the diagnosis of GS. Results. The patient was observed for 39 months, showing spontaneous resolution of the traction caused by the EM and improvement in visual acuity (VA), which was 20/80 at initial presentation, rising to 20/40 after follow-up period. Conclusions. The presence of EM in CHR-REP is a cause of reduction of visual acuity. Management of this condition is controversial; however, we would like to highlight that spontaneous resolution of the traction caused by EM is possible, resulting in recovery of VA.

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Section: Discussionsupporting

confidence: 63%

Combined Hamartoma of the Retina and Retinal Pigment Epithelium in a Patient with Gorlin Syndrome: Spontaneous Partial Resolution of Traction Caused by Epiretinal Membrane

Sánchez-Vicente

Contreras-Díaz

Rueda

et al. 2016

Case Reports in Ophthalmological Medicine

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“…[10][11][12][13][14] While surgical management in pediatric cases remains controversial, ERM peel to relieve vitreomacular traction in CHRRPE has been reported to improve visual function in select patients. 11,15,16 To our knowledge, only 4 cases of histopathologic evaluation of ERM overlying CHRRPE following vitrectomy have been reported to date, [17][18][19] likely given limitations in specimen handling, processing, and analysis. Unlike the case by Almony and colleagues, 17 no RPE cells were identified in our specimen.…”

Section: Discussionmentioning

confidence: 99%

A Case of a Combined Hamartoma of the Retina and RPE Concurrently Found in the Same Eye as Peripheral Astrocytic Hamartomas

Sherman

Schechet

Shapiro

et al. 2019

Journal of VitreoRetinal Diseases

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We report a case of a 7-year-old boy with neurofibromatosis 2 who was referred to our pediatric retina clinic for deteriorating vision of his left eye. Fundoscopy revealed a gray epiretinal and vitreous opacity extending to the fovea in the left eye. Optical coherence tomography (OCT) demonstrated an epiretinal membrane (ERM) with a distinct tissue plane and overlying vitreoretinal strands, consistent with combined hamartoma of the retina and retinal pigment epithelium (CHRRPE). Intraoperative OCT-guided pars plana vitrectomy and membrane peel were performed and the tissue was sent for histopathologic evaluation. Intraoperative scleral-depressed examination also revealed multiple elevated, white-gray, semitranslucent masses near the ora serrata, consistent with astrocytic hamartomas. Histopathologic analysis of the epiretinal tissue revealed glial origin. Recognition of any of these lesions in a young patient should prompt neurologic and genetic evaluation.

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“…5 Although observation of NF2-related epiretinal membranes is an option if the vision loss is mild, recent studies have shown gains in vision with early pars plana vitrectomy and epiretinal membrane peel. 6,7 Bonnin et al 7 reported operating on 13 patients with epiretinal membranes who were 12 years or younger. Of the 13 patients, 12 had improvement in visual acuity and the corrected visual acuity improved from an average of 20/160 to 20/40.…”

Section: Discussionmentioning

confidence: 99%

A Young Girl With Bilateral Atypical Epiretinal Membranes

2019

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An 8-year-old girl was referred to the vitreoretinal service for evaluation of bilateral macular lesions noted by her pediatric ophthalmologist. Bilateral lateral rectus muscle recession for exotropia was performed 4 years before this presentation. Medical history was otherwise unremarkable. The patient was born full term after a normal pregnancy and delivery, with normal growth assessments. The patient was performing well in school.On examination, her best-corrected visual acuity was 20/40 OD and 20/40 OS, which was stable from previous visits. Her pupils were round and reactive. There was a residual intermittent exotropia of 4 prism diopters bilaterally. Findings on slitlamp examination of the anterior segment were unremarkable. A single, 1-cm, oval, lightly pigmented macule with irregular borders was noted on her right upper arm. Dilated fundus examination revealed eccentric, yellow-clear, preretinal lesions in the maculas of both eyes. Optical coherence tomography revealed hyperreflective areas on the surface of the macula with a spiculated appearance, projecting anteriorly into the vitreous. There was an increase in retinal thickness and loss of the foveal contour in both eyes (Figure).

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Long-Term Outcome of Epiretinal Membrane Surgery in Young Children

Abstract: Even in very young children, surgery resulted in a significant long-term improvement. Children screening was essential for diagnosis and treatment in most cases.

Cited by 12 publications

References 10 publications

Combined Hamartoma of the Retina and Retinal Pigment Epithelium in a Patient with Gorlin Syndrome: Spontaneous Partial Resolution of Traction Caused by Epiretinal Membrane

Combined Hamartoma of the Retina and Retinal Pigment Epithelium in a Patient with Gorlin Syndrome: Spontaneous Partial Resolution of Traction Caused by Epiretinal Membrane

A Case of a Combined Hamartoma of the Retina and RPE Concurrently Found in the Same Eye as Peripheral Astrocytic Hamartomas

A Young Girl With Bilateral Atypical Epiretinal Membranes

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