Long-term nitrogen dioxide exposure and cause-specific mortality in the U.S. Medicare population

Eum, Ki-Do; Honda, Trenton; Wang, Bingyu; Kazemiparkouhi, Fatemeh; Manjourides, Justin; Pun, Vivian C.; Pavlu, Virgil; Suh, Helen

doi:10.1016/j.envres.2021.112154

Cited by 16 publications

(7 citation statements)

References 42 publications

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“…Importantly, this finding is consistent with the prior literature identifying disparities in T1DM glucose control and clinical outcomes by race, which underpins the broad impact of structural racism on health in racial and ethnic minority groups [27,28]. Consistent with this, the growing literature demonstrates that Black populations experience higher cause-specific mortality risk from air pollution exposure relative to other racial/ethnic groups [29][30][31]. These risk disparities underpin the broad and detrimental impacts of structural racism, and the resultant differential access to healthcare and differential exposure to environmental toxicants [32].…”

Section: Discussionsupporting

confidence: 87%

The Impact of Long-Term Air Pollution Exposure on Type 1 Diabetes Mellitus-Related Mortality among U.S. Medicare Beneficiaries

Honda

Kazemiparkouhi

Suh

2023

Toxics

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Background: Little of the previous literature has investigated associations between air pollution exposure and type 1 diabetes mellitus (T1DM)-related mortality, despite a well-established link between air pollution exposure and other autoimmune diseases. Methods: In a cohort of 53 million Medicare beneficiaries living across the conterminous United States, we used Cox proportional hazard models to assess the association of long-term PM2.5 and NO2 exposures on T1DM-related mortality from 2000 to 2008. Models included strata for age, sex, race, and ZIP code and controlled for neighborhood socioeconomic status (SES); we additionally investigated associations in two-pollutant models, and whether associations were modified by participant demographics. Results: A 10 μg/m3 increase in 12-month average PM2.5 (HR: 1.183; 95% CI: 1.037–1.349) and a 10 ppb increase in NO2 (HR: 1.248; 95% CI: 1.089–1.431) was associated with an increased risk of T1DM-related mortality in age-, sex-, race-, ZIP code-, and SES-adjusted models. Associations for both pollutants were consistently stronger among Black (PM2.5: HR:1.877, 95% CI: 1.386–2.542; NO2: HR: 1.586, 95% CI: 1.258–2.001) and female (PM2.5: HR:1.297, 95% CI: 1.101–1.529; NO2: HR: 1.390, 95% CI: 1.187–1.627) beneficiaries. Conclusions: Long-term NO2 and, to a lesser extent, PM2.5 exposure is associated with statistically significant elevations in T1DM-related mortality risk.

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Section: Discussionsupporting

confidence: 87%

The Impact of Long-Term Air Pollution Exposure on Type 1 Diabetes Mellitus-Related Mortality among U.S. Medicare Beneficiaries

Honda

Kazemiparkouhi

Suh

2023

Toxics

Self Cite

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“…Third, given the lack of clinical diagnoses regarding the cause of death [ 47 ], we failed to estimate associations between O 3 and cause-specific mortality and excluded accidental deaths from all-cause cases. However, highly similar C–R associations for non-accidental and all-cause mortality were reported in prior cohort studies of air pollution [ 48 , 49 ]. According to the Chinese Statistical Yearbook ( http://www.stats.gov.cn/tjsj/ndsj/ , accessed on 23 January 2023), the proportion of accidental deaths among the Chinese population between 2011 and 2018 remained low (range: 6.39–7.11%).…”

Section: Discussionsupporting

confidence: 75%

Excess mortality associated with high ozone exposure: A national cohort study in China

Yang

Wang

Sun

et al. 2023

Environmental Science and Ecotechnology

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“…One of the common air pollutants, primarily released during the combustion of fossil fuels, is nitrogen dioxide (NO 2 ). Even at low concentrations, NO 2 has the potential to cause a number of serious diseases, such as respiratory disease, cardiovascular disease, and cancer . Developing inexpensive high-performance NO 2 sensors is crucial for their effective use in a range of environmental assessment scenarios.…”

Section: Introductionmentioning

confidence: 99%

Structured Graphene Oxide/Reduced Graphene Oxide Interfaces for Improved NO₂ Sensing

Kumar

Dmitrieva

Meng

et al. 2023

ACS Appl. Nano Mater.

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Here, we demonstrate an improvement in sensitivity toward the NO2 analyte by varying the width ratio of adjacent graphene oxide (GO) and reduced graphene oxide (rGO) layers using the GO laser reduction technique. We evaluated changes brought by laser reduction in material morphology, structure, electrical characteristics, and sensing performance depending on the GO/rGO ratio, which we supported by density functional theory calculations. Our results indicate that the reduction of GO yields the appearance of a chemiresistive response to NO2. An optimum GO/rGO width ratio ensures high conductivity paired with good sorption capacity, allowing to achieve chemiresistive response of 18.1% toward 100 ppm of NO2 at 25 ± 1 °C and a limit of detection of 230 ppb. The improved chemiresistive response of GO/rGO sensors upon NO2 physisorption is due to an increase in sorption energy and improved charge transfer in the presence of NO2 at the sites corresponding to the individual epoxy and hydroxyl groups at the GO/rGO interface area when compared to fully reduced GO.

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Long-term nitrogen dioxide exposure and cause-specific mortality in the U.S. Medicare population

Cited by 16 publications

References 42 publications

The Impact of Long-Term Air Pollution Exposure on Type 1 Diabetes Mellitus-Related Mortality among U.S. Medicare Beneficiaries

The Impact of Long-Term Air Pollution Exposure on Type 1 Diabetes Mellitus-Related Mortality among U.S. Medicare Beneficiaries

Excess mortality associated with high ozone exposure: A national cohort study in China

Structured Graphene Oxide/Reduced Graphene Oxide Interfaces for Improved NO₂ Sensing

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Long-term nitrogen dioxide exposure and cause-specific mortality in the U.S. Medicare population

Cited by 16 publications

References 42 publications

The Impact of Long-Term Air Pollution Exposure on Type 1 Diabetes Mellitus-Related Mortality among U.S. Medicare Beneficiaries

The Impact of Long-Term Air Pollution Exposure on Type 1 Diabetes Mellitus-Related Mortality among U.S. Medicare Beneficiaries

Excess mortality associated with high ozone exposure: A national cohort study in China

Structured Graphene Oxide/Reduced Graphene Oxide Interfaces for Improved NO2 Sensing

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Product

Resources

About

Structured Graphene Oxide/Reduced Graphene Oxide Interfaces for Improved NO₂ Sensing