Long‐Term Mortality and Pacing Outcomes of Patients with Permanent Pacemaker Implantation after Cardiac Surgery

Raza, Sadi; Li, Jianming; John, Ranjit; Chen, Lin Y.; Tholakanahalli, Venkatakrishna N.; Mbai, Mackenzie; Adabag, Selçuk

doi:10.1111/j.1540-8159.2010.02972.x

Cited by 69 publications

(70 citation statements)

References 35 publications

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“…[2][3][4][19][20][21] In contrast to these results, we failed to find any deleterious effect of PPI on mortality or heart failure status in patients undergoing TAVI, even in patients with left ventricular dysfunction at baseline. However, these finding are consistent with prior studies in the cardiac surgery field, 22 as well as with some prior smaller TAVI series. [8][9][10][11] Results from the Dual Chamber and VVI Implantable Defibrillator (DAVID) trial, Mode Selection Trial (MOST), and Multicenter Automatic Defibrillator Implantation Trial II (MADIT-II) showed that the deleterious impact of pacing on heart failure or mortality depends on cumulative percent time of ventricular pacing.…”

Section: Ppi After Tavi and Clinical Outcomessupporting

confidence: 83%

Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation

et al. 2014

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T ranscatheter aortic valve implantation (TAVI) has become the treatment of choice for patients with aortic stenosis who are considered to be nonoperable and a good alternative for those at high surgical risk.1 However, the occurrence of some periprocedural complications remains a concern. The need for permanent pacemaker implantation (PPI) after the procedure is one of the most frequent complications associated with TAVI, with an overall incidence of ≈15% (≈25% and 7% after TAVI with self-expandable valves [SEVs] and balloon-expandable valves [BEVs], respectively). 1 Clinical Perspective on p 1243Strong evidence supports the potential negative impact of right ventricular apical pacing, which has been associated with an increased rate of the combined end point of mortality and rehospitalization for heart failure in patients with left ventricular dysfunction, 2-4 ventricular tachyarrhythmias, 5,6 and pacing-induced cardiomyopathy in patients without overt structural heart disease. 7 However, evidence for the clinical impact of PPI after TAVI remains scarce and based on small Background-Very few data exist on the clinical impact of permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation. The objective of this study was to assess the impact of PPI after transcatheter aortic valve implantation on late outcomes in a large cohort of patients. =0.121). Conclusions-The need for PPI was a frequent complication of transcatheter aortic valve implantation, but it was not associated with any increase in overall or cardiovascular death or rehospitalization for heart failure after a mean follow-up of ≈2 years. Indeed, 30-day PPI was a protective factor for the occurrence of unexpected (sudden or unknown) death.

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Section: Ppi After Tavi and Clinical Outcomessupporting

confidence: 83%

Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation

et al. 2014

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“…Survival was assessed using the electronic medical records, social security death index and the VA Beneficiary Identification Records Locator Subsystem 10 11. In patients who died, the cause of death was ascertained from the death certificates.…”

Section: Methodsmentioning

confidence: 99%

Long-term follow-up of older patients with Mobitz type I second degree atrioventricular block

Coumbe

Naksuk

Newell

et al. 2012

Heart

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“…Multivariable logistic regression included the time unit (day vs. night or weekday vs. weekend), mortality risk estimate and priority of the operation (elective vs. urgent or emergent). The method of adjusting for patients' risk by including the mortality risk estimate in the multivariable model has been validated before [14-16]. Indicator variables were used when examining the mortality rate in relation to the priority surgery and to the months of the year.…”

Section: Methodsmentioning

confidence: 99%

Variation of mortality after coronary artery bypass surgery in relation to hour, day and month of the procedure

Coumbe

Kuskowski

Ağırbaşlı

et al. 2011

BMC Cardiovasc Disord

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BackgroundMortality and complications after percutaneous coronary intervention is higher when performed after regular duty hours due to challenging patient characteristics, inferior processes of care and limited resources. Since these challenges are also encountered during coronary artery bypass graft (CABG) surgery that is performed after regular work hours, we assessed whether hour and day of procedure influenced mortality after CABG.MethodsWe studied 4,714 consecutive patients who underwent CABG at the Minneapolis Veterans Administration (VA) Medical Center between 1987 and 2009. We compared postoperative (30-day) mortality rates in relation to hour and day in which the operation was performed.ResultsOperations performed on weekends and after 4 PM had higher risk patients (p < 0.0001) and were more likely to be emergent (p < 0.0001), require intra-aortic balloon pump support (p < 0.0001) and result in postoperative complications (p < 0.0001) compared to those at regular work hours. Mortality was significantly higher when CABG was performed on weekends compared to weekdays (9.4% versus 2.5%; odds ratio (OR) 4.1, 95% confidence interval (CI) 1.6 to 10.4, p = 0.003), and after 4 PM compared to between 7 AM-4 PM (6.2% versus 2.2%; OR 2.9, 95% CI 1 to 8, p = 0.049). In multivariable analysis, when adjusted for the urgency of the operation and the VA estimated mortality risk score, these associations were no longer statistically significant.ConclusionsMortality after CABG is higher when surgery is performed on the weekends and after 4 PM. These variations in mortality were related to higher patient risk, and urgency of the operation rather than external factors.

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Long‐Term Mortality and Pacing Outcomes of Patients with Permanent Pacemaker Implantation after Cardiac Surgery

Abstract: The majority of patients who require PPM after cardiac surgery are not PPM dependent in the long term. Requiring a PPM after surgery is not associated with long-term mortality after adjustment for patient-related risk factors and cardiac surgical procedure.

Cited by 69 publications

References 35 publications

Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation

Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation

Long-term follow-up of older patients with Mobitz type I second degree atrioventricular block

Variation of mortality after coronary artery bypass surgery in relation to hour, day and month of the procedure

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