Long-Term Monitoring of Renal Function in Poly-Traumatized Intensive Care Patients

Dehne, M. G.; Sablotzki, Armin; Mühling, J.; Dehne, Karl L.; Röhrig, Rainer; Hempelmann, G.

doi:10.1081/jdi-120006776

Cited by 3 publications

(5 citation statements)

References 22 publications

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“…Fifteen of the included articles reported data on the individual causes of death [ 12 – 17 , 19 – 23 , 32 , 34 , 36 , 41 ]. One paper provided date from five independent time periods leading to a total of 19 data points [ 17 ].…”

Section: Resultsmentioning

confidence: 99%

“…[62] Not mentioned Aufmkolk et al [ 14 ] ≥ 3 failing organs for ≥ 3 sequential days Not defined Positive blood culture + ≥ 2 of the following: 36 < Temp. > 38; 4000 < leukocytes > 12,000 or left shift > 10%; heart rate > 90/min; respiratory rate > 20/min or pCO2 < 32 mmHg Dereeper et al [ 15 ] Acute renal failure was defined as a blood urea nitrogen (BUN) > 40 and/or creatinine > 2 mg/dl; hepatic failure by a bilirubin > 2 mg/dl or transaminases > 80 IU/l; coagulation abnormalities by a platelet count < 100,000/mm 3 with either a prothrombin time < 60% of the normal value or an activated partial thromboplastin time > 80 s. Acute respiratory failure by a PaO2/FiO2 ratio < 250 mmHg or requirement for mechanical ventilation for > 24 h for a respiratory problem Not mentioned Nast-Kolb et al [ 17 ] ≥ 2 failing organs for ≥ 3 days (central nervous system not included) European-American Consensus Conference on ARDS A source of infection (positive blood culture) plus two or more of the following parameters: temperature 36 (°C) or 38; leukocytes 4000 (nL) or 12,000 or immature neutrophils 10%; heart rate > 90 (beats/min); and respiratory rate > 20 (breaths/min) or pCO2 > 32 mm Hg Hadfield et al [ 16 ] Not defined Not defined Not defined Ruiz et al [ 41 ] Not defined Not defined Sequential organ failure assessment (SOFA) score Ciesla et al [ 19 ] Denver MOF scoring system Not defined Not defined Zhang et al [ 20 ] Not defined Not defined Not defined Di Saverio et al [ 22 ] Not defined Not mentioned Not defined Chen et al [ 21 ] Not defined Not defined Not defined Dehne et al [ 34 ] Not defined Not mentioned Not mentioned Van Wessem and Leenen [ 23 ] Denver multiple orga...…”

Section: Methodsmentioning

confidence: 99%

“…Most studies were retrospective, although data was sometimes collected prospectively in a trauma registry. There was no indication for selection bias in all 30 studies except for three [33,34,37]. Either patients were not consecutively included or the inclusion process was not clearly described in these articles.…”

Section: Quality Of the Included Articlesmentioning

confidence: 99%

“…The four most common causes were selected: brain injury, MODS, hemorrhage, and sepsis. Fourteen articles reported complete data and were included in this analysis (North America (USA): n = 1 [ 19 ], South America: n = 1 [ 41 ], Asia: n = 2 [ 20 , 21 ], Europe: n = 10 [ 12 – 17 , 22 , 23 , 32 , 34 ]). Again, weighted averages were calculated.…”

Section: Appendix 1 Search Stringsmentioning

confidence: 99%

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Global changes in mortality rates in polytrauma patients admitted to the ICU—a systematic review

et al. 2020

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Background Many factors of trauma care have changed in the last decades. This review investigated the effect of these changes on global all-cause and cause-specific mortality in polytrauma patients admitted to the intensive care unit (ICU). Moreover, changes in trauma mechanism over time and differences between continents were analyzed. Main body A systematic review of literature on all-cause mortality in polytrauma patients admitted to ICU was conducted. All-cause and cause-specific mortality rates were extracted as well as trauma mechanism of each patient. Poisson regression analysis was used to model time trends in all-cause and cause-specific mortality. Thirty studies, which reported mortality rates for 82,272 patients, were included and showed a decrease of 1.8% (95% CI 1.6–2.0%) in all-cause mortality per year since 1966. The relative contribution of brain injury-related death has increased over the years, whereas the relative contribution of death due to multiple organ dysfunction syndrome (MODS), acute respiratory distress syndrome, and sepsis decreased. MODS was the most common cause of death in North America, and brain-related death was the most common in Asia, South America, and Europe. Penetrating trauma was most often reported in North America and Asia. Conclusions All-cause mortality in polytrauma patients admitted to the ICU has decreased over the last decades. A shift from MODS to brain-related death was observed. Geographical differences in cause-specific mortality were present, which may provide region-specific learning possibilities resulting in improvement of global trauma care.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Quality Of the Included Articlesmentioning

confidence: 99%

Section: Appendix 1 Search Stringsmentioning

confidence: 99%

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Global changes in mortality rates in polytrauma patients admitted to the ICU—a systematic review

et al. 2020

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“…Three patients with multiple injuries on the first day were falsely classified into the upper GI bleed group. This resulted from the fact that massive bleeding requires intensive fluid transfusions (3,14,23,(44)(45)(46)(47) and comprises the initial dominating disorder found in patients with multiple injuries. As a result of distinct inflammatory response found in both diseases, two patients suffering from acute pancreatitis were falsely classified into the MOC group, (27)(28)(29)(30)(31).…”

Section: Discussionmentioning

confidence: 99%

Models of Certain Types of Surgical Shock Based on the Assessment of Selected Critical Parameters

Budzyński

Brongel

Nazimek

et al. 2007

Polish Journal of Surgery

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The aim of the study was to devise models that describe three types of surgical shock based on a set of simple biochemical and clinical parameters and establish a method of assigning new patients to each surgical shock scenario. Material and methods. Prospective analysis included patients hospitalized in IInd Chair of Surgery from 2001 to 2005 who belonging to the following groups: multiple injuries (at least 7 points according to LSO), upper GI bleeding (in patients requiring blood transfusions during first day) and severe acute pancreatitis (at least 3 rd degree according to Trapnell's scale). A set of nineteen parameters was evaluated on the first, fourth and seventh day in every patient. Discrimination analysis was used for statistical analysis with calculation of Mahalanobis squared distances between groups that reflect their reciprocal differences. Discrimination functions were calculated allowing the assignment of a new observation to one of the models. Eventually, reliability of categorizing patients to the studied groups was evaluated. Results. Differences among the groups -reflected by Mahalanobis squared distances -proved statistically significant in every studied day. Overall, the ratio of proper classifications according to discrimination functions equaled about 87%. The most common mistake in categorizing was observed in groups of multiple injuries and acute pancreatitis -due to similar pathophysiological processes leading through SIRS to MOF. Conclusions. The abovementioned results indicate that the presented models can be successfully used in diagnostic processes, especially in emergency cases. The set of clinical and biochemical parameters used is simple and easy to obtain even in non-specialized centers. Key words: multiple injuries, acute pancreatitis, upper GI bleeding, discrimination analysis POLSKI PRZEGLĄD CHIRURGICZNY 10.2478/v10035-007-0054-2 2007 Significant effort was made to create a uniform system for the assessment of patient clinical status -regardless of the underlying disease, which would serve as a help for making therapeutic decisions and evaluating prognosis. For this purpose, many scales assessing the severity of homeostatic disturbances were created. In spite of their abundance, there is still a lack of single scale that can quickly, precisely and unequivocally set proper diagnosis in different life-threatening conditions. Moreover, many from the recently devised scales are based on parameters that require significant time or sophisticated techniques to obtain results (1-11). A system established to assess patient clinical status and aid in making proper diagnosis -especially in situations requiring immediate interventions -could improve the process of initial triage in Emergency Departments with limited access to highly specialized diagnostic techniques.The aim of this study was to create models of response in three commonly found settings of surgical and traumatological shock based on a set of selected critical parameters.

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Kidney-Specific Proteins in Elderly Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass: Retracted

Boldt¹,

Brenner²,

Lang³

et al. 2003

Anesthesia & Analgesia

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Long-Term Monitoring of Renal Function in Poly-Traumatized Intensive Care Patients

Cited by 3 publications

References 22 publications

Global changes in mortality rates in polytrauma patients admitted to the ICU—a systematic review

Global changes in mortality rates in polytrauma patients admitted to the ICU—a systematic review

Models of Certain Types of Surgical Shock Based on the Assessment of Selected Critical Parameters

Kidney-Specific Proteins in Elderly Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass: Retracted

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