Long‐term macular function in eyes with central serous chorioretinopathy

Baran, Nergis V; Gürlü, Vuslat; Esgin, Haluk

doi:10.1111/j.1442-9071.2005.01027.x

Cited by 112 publications

(74 citation statements)

References 14 publications

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“…Overall, these findings indicate the persistence of metamorphopsia, irrespective of the resolution of SRF, a decrease of OCT retinal thickness and improvements in the mean MP retinal sensitivity and visual acuity. This seems to be consistent with a study reporting that despite spontaneous complete recovery of visual acuity after an acute episode of CSC, the majority of patients experience metamorphopsia in the long-term follow-up [28]. …”

Section: Discussionsupporting

confidence: 78%

Short-Term Retinal Sensitivity and Metamorphopsia Changes following Half-Fluence Photodynamic Therapy in Central Serous Chorioretinopathy

et al. 2016

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Purpose: The aim of this study was to investigate the short-term retinal sensitivity and metamorphopsia changes after half-fluence photodynamic therapy (PDT) in patients with central serous chorioretinopathy (CSC). Methods: Patients with acute CSC and evidence of angiographic leakage and subretinal fluid on optical coherence tomography (OCT) were enrolled. Before, and 1 week (W-1) and 2 months (M-2) after PDT, all patients underwent best-corrected visual acuity, enhanced depth imaging OCT, microperimetry (MP) and preferential hyperacuity perimetry (PHP). We considered ‘affected' the Early Treatment of Diabetic Retinopathy Study (ETDRS) sectors showing a mean retinal thickness greater than 350 μm on the baseline OCT thickness map. MP retinal sensitivity, PHP ‘score' and retinal thickness were measured in each ETDRS ‘affected sector'. Functional correlation between MP and PHP was also investigated. Results: Twelve eyes of 12 patients were included. MP and PHP correlated with each other at baseline (p = 0.04) but not at W-1 (p = 0.12) and M-2 (p = 0.05). Mean MP retinal sensitivity slightly improved from 12.9 ± 5.0 dB at baseline to 14.5 ± 4.7 dB at M-2 (p = 0.2). The PHP score changed from 0.33 at baseline to 0.32 at M-2 (p = 0.3). In the ETDRS ‘affected sectors', MP retinal sensitivity improved significantly from 12.9 ± 5.0 dB at baseline to 14.5 ± 4.7 dB at M-2 (p = 0.03), whereas the PHP score did not show significant changes over time. Conclusion: Half-fluence PDT achieved short-term improvement in the sensitivity of the retinal ‘affected sectors' but did not influence metamorphopsia as measured on PHP in patients with acute CSC.

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Section: Discussionsupporting

confidence: 78%

Short-Term Retinal Sensitivity and Metamorphopsia Changes following Half-Fluence Photodynamic Therapy in Central Serous Chorioretinopathy

et al. 2016

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“…Acute CSC is a self-limited disease and SRF usually resolves spontaneously within 3-4 months after the beginning of symptoms. 14 Recurrence rate reported in the literature differs largely because of the heterogeneity of follow-up periods within studies. Hence, recurrence rate of acute CSC was reported to vary between 15 and 50% in spontaneously resolved patients.…”

Section: Discussionmentioning

confidence: 99%

The time of resolution and the rate of recurrence in acute central serous chorioretinopathy following spontaneous resolution and low-fluence photodynamic therapy: a case–control study

Özkaya

Alkın

Özveren

et al. 2016

Eye

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Purpose To evaluate the resolution time and the recurrence rate of acute central serous chorioretinopathy (CSC) after spontaneous resolution and low-fluence photodynamic therapy (PDT). Methods Case-control study: The CSC patients who were admitted to our clinic for the first time were included. No treatment was given during the first 6 months. Patients were treated with PDT after 6 months from the initial signs of the disease, if they did not show any sign of resolution. The patients who showed a significant decrease in subretinal fluid after month 6 were not scheduled for PDT. The primary outcomes were the resolution time and the recurrence rate after the first episode. Secondary outcome measures were the change in BCVA and CRT during the follow up. Results A total of 77 consecutive eyes of 77 patients were included, 41 eyes (53.2%) with spontaneously resolved CSC and 36 eyes (46.8%) with PDT-treated CSC. The initial resolution time was 4.1 ± 3.2 months in spontaneous resolution group, and 8.1 ± 0.8 months in PDT group, respectively (Po0.001). The recurrence rate was 51.2% in spontaneous resolution group, and 25% in PDT group (P = 0.01). The change in BCVA from baseline to the last follow-up visit was statistically significant in both groups (P = 0.002, P = 0.003, respectively). The change in CRT from baseline to the last follow up was also statistically significant in both groups (P = 0.002, P = 0.003, respectively). Conclusions The recurrence rate of acute CSC was lower in PDT-treated patients than the spontaneously resolved patients.

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“…8,9 However, there may be residual symptoms such as decreased retinal sensitivity, metamorphopsia, decreased VA, and central scotoma. [10][11][12] In chronic cases, visual function declines because unresolved retinal detachment can lead to RPE and photoreceptor damage. 13,14 The usefulness of microperimetry (MP) in evaluating retinal sensitivity (RS) and central retinal field function is well known in resolved CSC.…”

Section: Introductionmentioning

confidence: 99%

Retinal sensitivity assessed by microperimetry and corresponding retinal structure and thickness in resolved central serous chorioretinopathy

Chung

et al. 2014

Eye

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Purpose To investigate the relationship between retinal sensitivity (RS) assessed by microperimetry (MP) and retinal structural changes in patients with resolved central serous chorioretinopathy (CSC). Methods Spectral domain optical coherence tomography (OCT) examination and MP tests were performed in patients with resolved CSC. Point-to-point correlation was performed between RS and corresponding retinal structural changes using Pearson's correlation analysis. In addition, in a 1-mm zone in the central fovea, a correlation was calculated between the mean RS and the mean central retinal thickness (CRT). Results Eighty-four eyes were analyzed. The total number of MP test points was 1092 (84 eyes Â 13 points). The mean RS and retinal point thickness (RPT) of all test points were 13.53±3.84 dB and 208.6±48.0 mm, respectively. The RS and RPT were significantly decreased in the test points with loss of the ellipsoid portion of the inner segments (EPIS) (Po0.0001). Within the 1-mm foveal center zone, there was a significant correlation between mean RS and mean CRT (r ¼ 0.432, Po0.0001) and between RS and the corresponding RPT (r ¼ 0.339, Po0.0001). Conclusion RS was dependent on the status of the EPIS in patients with resolved CSC. The correlation between mean RS and mean CRT was compatible with the point-topoint correlation between RS and the corresponding RPT.

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Long‐term macular function in eyes with central serous chorioretinopathy

Abstract: Patients with unilateral CSCR were observed to have long-term bilateral colour discrimination defects, and eyes with clinical CSCR were determined to have central relative scotoma and loss of contrast sensitivity.

Cited by 112 publications

References 14 publications

Short-Term Retinal Sensitivity and Metamorphopsia Changes following Half-Fluence Photodynamic Therapy in Central Serous Chorioretinopathy

Short-Term Retinal Sensitivity and Metamorphopsia Changes following Half-Fluence Photodynamic Therapy in Central Serous Chorioretinopathy

The time of resolution and the rate of recurrence in acute central serous chorioretinopathy following spontaneous resolution and low-fluence photodynamic therapy: a case–control study

Retinal sensitivity assessed by microperimetry and corresponding retinal structure and thickness in resolved central serous chorioretinopathy

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