Long‐term insulin resistance is associated with frailty, frailty progression, and cardiovascular disease
Zezhi Ke,
Han Wen,
Rihua Huang
et al.
Abstract:BackgroundInsulin resistance and diabetes are associated with an increased risk of frailty, and frailty is associated with cardiovascular disease and premature mortality. We aim to investigate the impact of long‐term insulin resistance trajectories on future frailty and cardiovascular risk among young adults.MethodsIn total, 3168 participants with a 30‐year follow‐up period. The baseline period covered the first 15 years as the exposure period. Insulin resistance was determined using the homeostasis model asse… Show more
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