“…3,7,8 It could be postulated that, similar to various other complex regional pain syndromes, persistent repetitive stimulation of central pain pathways over time results in autonomous signal generators that could confound results. 4,9 However, to the best of our knowledge, our study is the first to show that this association was more closely associated with age. Each additional month of symptoms in the patient group Ն40 years was associated with a significant decrease in successful outcome.…”