2006
DOI: 10.1097/01.ico.0000243961.52769.5f
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Long-Term Follow-Up of the Corneal Endothelium After Artisan Lens Implantation for Unilateral Traumatic and Unilateral Congenital Cataract in Children

Abstract: Endothelial cell loss 10.5 years after iris-fixated IOL implantation for traumatic cataract was substantial and related to the length of the corneal scar of the original trauma. In children operated on for congenital cataract, no difference was found in CECD in the operated and unoperated eyes 9.5 years after Artisan aphakia IOL implantation.

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Cited by 36 publications
(25 citation statements)
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“…5 Endothelial cell loss is also found to be limited in the long term after Artisan aphakia IOL implantation in congenital and juvenile cataract cases. 6,7 More than 12 years after surgery, endothelial cell densities in our cases were within the expected range for eyes without crystalline lens surgery; however, compared to the control eyes and to normal subjects in the literature, we found a higher coefficient of variation of cell size and a lower percentage of hexagonal cells. 8 These changes might be related to the IOL; however, changes in morphology are also reported in nonoperated eyes from patients with Marfan syndrome, with the most prominent changes in eyes with lens dislocation 9 and in both eyes of one control patient in the current study.…”
Section: Discussionsupporting
confidence: 39%
“…5 Endothelial cell loss is also found to be limited in the long term after Artisan aphakia IOL implantation in congenital and juvenile cataract cases. 6,7 More than 12 years after surgery, endothelial cell densities in our cases were within the expected range for eyes without crystalline lens surgery; however, compared to the control eyes and to normal subjects in the literature, we found a higher coefficient of variation of cell size and a lower percentage of hexagonal cells. 8 These changes might be related to the IOL; however, changes in morphology are also reported in nonoperated eyes from patients with Marfan syndrome, with the most prominent changes in eyes with lens dislocation 9 and in both eyes of one control patient in the current study.…”
Section: Discussionsupporting
confidence: 39%
“…The longer interval in these cases may not only force corneal endothelial cells into overexposure to inflammatory mediators, but also aggravate synechiae that need a more complex procedure in anterior chamber during secondary operation. Primary cataract type [31] and high intraocular pressure (IOP) [32,33], as previously reported, were important factors accompanied by corneal endothelial cell loss. However, the percentage of cell loss in congenital cataract cases was similar to the traumatic ones.…”
Section: Discussionmentioning
confidence: 78%
“…The substantial cell loss in eyes after surgery for traumatic cataract seems to be primarily caused by damage due to the perforating trauma and not by the presence of the Artisan aphakia IOL. 20 Three of the six patients with traumatic cataract (Cases 2, 4, and 5; only those children who received a standard Artisan IOL model Photographs of the endothelium were obtained at last follow-up in this present study. Serial cell counts were not available.…”
Section: Discussionmentioning
confidence: 99%