“…15 Treatment with other modalities, including brachytherapy, has been undertaken in limited patient groups, with some success. 16,17 Sirolimus-coated stents have shown a significant reduction in the rate of in-stent stenosis in native coronary artery disease. In the first clinical study published (the RAVEL study), none of the patients receiving the sirolimus-coated stents had Ͼ50% stenosis at 6 months compared with 26.6% of patients in the conventional group.…”