Long-term Follow-up of a Fenestrated Amplatzer Atrial Septal Occluder in Pulmonary Arterial Hypertension

Althoff, Till; Knebel, Fabian; Panda, Alexander; McArdle, John R.; Gliech, V.; Franke, I; Witt, Christian; Baumann, Gert; Borges, Adrian C.

doi:10.1378/chest.07-1222

Cited by 46 publications

(34 citation statements)

References 7 publications

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“…The recommended technique is graded balloon dilation atrial septostomy, which produces equivalent improvements in haemodynamics and symptoms but reduced risk compared with the original blade technique. Other techniques are considered experimental [255].…”

Section: Balloon Atrial Septostomymentioning

confidence: 99%

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

et al. 2015

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Guidelines summarize and evaluate all available evidence on a particular issue at the time of the writing process, with the aim of assisting health professionals in selecting the best management strategies for an individual patient with a given condition, taking into account the impact on outcome, as well as the risk–benefit ratio of particular diagnostic or therapeutic means. Guidelines and recommendations should help health professionals to make decisions in their daily practice. However, the final decisions concerning an individual patient must be made by the responsible health professional(s) in consultation with the patient and caregiver as appropriate.

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Section: Balloon Atrial Septostomymentioning

confidence: 99%

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

et al. 2015

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“…This approach has been followed by other investigators [22][23][24][25][26][27]. Both a high long-term occlusion rate [25] and long-term patency of these devices has been reported [26,27]. At present, it is difficult to anticipate the long-term risk/benefit of this approach.…”

Section: Discussionmentioning

confidence: 99%

Effect of atrial septostomy on the survival of patients with severe pulmonary arterial hypertension

Sandoval¹,

Gaspar²,

Peña³

et al. 2011

Eur Respir J

120

100

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Atrial septostomy (AS) is a palliative treatment for right ventricular failure from severe pulmonary arterial hypertension (PAH). We sought to investigate the effect of AS, alone or combined with PAH-specific pharmacotherapy, on the survival of patients with PAH.We performed a retrospective analysis of the functional and haemodynamic changes in patients with PAH following AS, and long-term survival characteristics for the whole group and separately for the subgroup who received post-procedural pharmacotherapy. 50 procedures performed in 34 patients (mean¡SD age 35¡10 yrs) resulted in haemodynamic and symptomatic improvement in most of the patients. Only one (2%) procedure-related death occurred. Due to spontaneous closure of the defect, AS was repeated in 10 patients. In 21 patients, AS was the only form of treatment, while 11 received additional pharmacotherapy after AS. During follow-up (58.5¡38 months), 21 patients died; median survival of the group was 60 months (95% CI 43-77 months). Median survival for patients on pharmacotherapy additional to AS was 83 months (95% CI 57-109 months), which was better than that for patients with AS alone (53 months, 95% CI 39-67 months) (log-rank 6.52; p50.010).In selected patients with PAH, AS is a safe and effective intervention that exerts a beneficial impact on long-term survival. Survival appears to be improved when AS is combined with PAHspecific pharmacotherapy.

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“…Also, for endovascular procedures more and more common (Althoff, Knebel et al 2008), measurements taken on prototypes corresponding to patients could open new perspectives. For the planning procedure of these interventions, the assessment of collisions problems as well as the adequacy of customed implants might be performed on heart models (Harrison, Estefan-Ventura et al 2007).…”

Section: Other Applications and Perspectives Of Rapid Prototyping In mentioning

confidence: 99%

Rapid Prototyping for Training Purposes in Cardiovascular Surgery

Abdel-Sayed¹,

Segesser²

2011

Advanced Applications of Rapid Prototyping Technology in Modern Engineering

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Long-term Follow-up of a Fenestrated Amplatzer Atrial Septal Occluder in Pulmonary Arterial Hypertension

Cited by 46 publications

References 7 publications

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

Effect of atrial septostomy on the survival of patients with severe pulmonary arterial hypertension

Rapid Prototyping for Training Purposes in Cardiovascular Surgery

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