Long Term Follow Up of Cutaneous Sinus Histiocytosis (Rosai-Dorfman Disease)

Abstract

Rosai-Dorfman disease is a benign histiocytic proliferative disorder of unknown etiology with cutaneous variants clinically presenting with painless cervical lympadenopathy, fever, leukocytosis and other systemic findings.1 Although the skin is the most common extranodal site, rare purely cutaneous forms of the disease exist and diagnosing such case rests solely on histopathologic findings.2 We report a case with a fifteen year follow up period of this uncommon disorder and describe itsclinical course marked by multiple episodic recurrences.