Long Term Favorable Prognostic Value of Negative Treadmill Echocardiogram in the Setting of Abnormal Treadmill Electrocardiogram: A 95 Month Median Duration Follow-Up Study

The value of negative stress echocardiography in predicting cardiovascular events among adults with no known coronary disease

“…26 The results of the report by Chung et al revealed diabetes as a predictor of adverse outcomes in patients with normal ESE and no history of CAD. 20 However, diabetes was not independently predicted adverse outcome in the study of Barbieri et al on patients with normal ESE 22 as well as in the study of Al-Mallah et al 25 and McCully et al 21 Unlike the results of our study regarding the subgroup of patients with normal DSE, Chaowalit et al found diabetes as an independent predictor of adverse outcomes. It should be noted that unlike our study, patients who did not reach the target heart rate were included in their study sample.…”

“…27 In the study of Al-Mallah et al on patients with normal ESE, hypertension, diabetes, and smoking were not independent factors of long-term MACE in multivariate Cox regression analysis. 25 In the study of Velasco del Castillo et al on patients without ischemia in ESE, smoking, dyslipidemia, hypertension, and diabetes were associated with a higher risk of adverse events in univariate analysis but lost their significance in multivariate analysis after adjustment for other stress echocardiography variables. 24…”

Exercise Standards for Testing and Training

“…Exercise capacity is a powerful diagnostic and prognostic marker. 75,211,[243][244][245][246] In a study of 135 women who underwent stress testing and subsequent angiography, exercise capacity was among the best stress testing variables for predicting the presence of CAD, and it improved the sensitivity and specificity of exercise testing when added to ST-segment depression. 246 In another study of both men and women, the achievement of ≥10 METs was associated with a lower prevalence of ischemia as evaluated by SPECT imaging than was the achievement of <7 METs (0.4% versus 7.1%, P<0.001).…”

Clinical outcomes of discordant exercise electrocardiographic and echocardiographic findings compared with concordant findings in patients with chest pain and no history of coronary artery disease

“…Some researchers [7,12,13] have also insisted on its incremental prognostic value over clinical parameters and other image studies such as 201 Thallium SPECT. On contrary, other researchers have suggested that incremental prognostic value of ST changes is absent over clinical parameters [4,6,14,15] or exercise capacity has better prognostic value than ST change. [15,16] Comparative evaluation of diagnostic and prognostic values of discordant ECG and echocardiographic (Echo) findings compared with concordant ECG and Echo findings on treadmill exercise echocardiography would help identify whether exercise Echo has additional benefits over exercise ECG in clinical decision-making and whether discordant findings have different clinical outcomes.…”