Long-term exposure to transportation noise and risk of type 2 diabetes: A cohort study

Sørensen, Mette; Hvidtfeldt, Ulla Arthur; Poulsen, Aslak Harbo; Thygesen, Lau Caspar; Khan, Jibran; Raaschou‐Nielsen, Ole

doi:10.1016/j.envres.2022.114795

Cited by 10 publications

(7 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…61 Interestingly, 2 studies have investigated the effects of road traffic noise at both the most exposed façade (standard noise measure) and the least exposed façade, considered to be a proxy for bedroom noise exposure, as people often chose to sleep in a room facing away from a busy street. 34,62 These 2 studies found more potent effects of noise at the least exposed façade than the most exposed façade, suggesting that for diabetes, the effects of noise on sleep are a potential mechanism. Furthermore, noise-induced endothelial dysfunction is suggested to contribute to the adverse metabolic effects of noise.…”

Section: Diabetes and Obesitymentioning

confidence: 99%

Transportation Noise Pollution and Cardiovascular Health

Münzel,

Molitor,

Kuntic

et al. 2024

Circulation Research

Self Cite

View full text Add to dashboard Cite

Epidemiological studies have found that transportation noise increases the risk for cardiovascular morbidity and mortality, with solid evidence for ischemic heart disease, heart failure, and stroke. According to the World Health Organization, at least 1.6 million healthy life years are lost annually from traffic-related noise in Western Europe. Traffic noise at night causes fragmentation and shortening of sleep, elevation of stress hormone levels, and increased oxidative stress in the vasculature and the brain. These factors can promote vascular (endothelial) dysfunction, inflammation, and arterial hypertension, thus elevating cardiovascular risk. The present review focusses on the indirect, nonauditory cardiovascular health effects of noise. We provide an updated overview of epidemiological research on the effects of transportation noise on cardiovascular risk factors and disease, and mechanistic insights based on the latest clinical and experimental studies and propose new risk markers to address noise-induced cardiovascular effects in the general population. We will discuss the potential effects of noise on vascular dysfunction, oxidative stress, and inflammation in humans and animals. We will elaborately explain the underlying pathomechanisms by alterations of gene networks, epigenetic pathways, circadian rhythm, signal transduction along the neuronal-cardiovascular axis, and metabolism. We will describe current and future noise mitigation strategies. Finally, we will conduct an overall evaluation of the status of the current evidence of noise as a significant cardiovascular risk factor.

show abstract

Section: Diabetes and Obesitymentioning

confidence: 99%

Transportation Noise Pollution and Cardiovascular Health

Münzel,

Molitor,

Kuntic

et al. 2024

Circulation Research

Self Cite

View full text Add to dashboard Cite

show abstract

“…A limitation of administrative studies, such as the above-described Danish study, is the lack of information on lifestyle factors. The degree of residual confounding from lifestyle in studies with access to only sociodemographic covariates was recently investigated in a Danish cohort study of 286,151 persons of whom 7574 developed diabetes during follow-up [ 117 ]. This study found a HR of 1.07 (95 % CI: 1.04; 1.10) per 10 dB L den Max in a crude model adjusted for age, sex, and year.…”

Section: Health Impact Of Transportation Noisementioning

confidence: 99%

“…Each outcome was also independently associated with higher levels of noise intermittency, evaluated using intermittency ratio (IR%), most strongly for heart failure (1.053 (1.050–1.055) for IR ≥ 75 % (4th quintile) vs. <25 % (reference, 1st quintile). Thacher et al, 2021 [ 115 ] , Sørensen et al, 2023 [ 117 ] Type 2 diabetes A nationwide cohort study from Denmark of 3.56 million persons and >230,000 cases found noise to be associated with higher risk of type 2 diabetes, with HRs of 1.05 (1.04, 1.05) and 1.09 (1.08, 1.10) for road traffic noise at the most and least exposed façade, respectively, and 1.03 (1.02, 1.04) and 1.02 (1.01, 1.03) for railway noise at the most and least exposed façade, respectively. Exposure-response curves starting from 35 to 40 dB indicated no threshold below which noise was not harmful.…”

Section: Introductionmentioning

confidence: 99%

Health position paper and redox perspectives - Disease burden by transportation noise

Sørensen,

Pershagen,

Thacher

et al. 2024

Redox Biology

Self Cite

View full text Add to dashboard Cite

“…Transportation noise, particularly from road and railway sources, has been suggested to be associated with diabetes mellitus type 2 (T2DM), a metabolic disease characterized by insulin resistance and impaired glucose regulation. 19 The connection between noise and diabetes is multifaceted and involves several physiological and behavioral pathways. First, noise‐induced psychological stress disturbs the hypothalamic–pituitary–adrenal axis, leading to an increased release of cortisol, a stress hormone.…”

Section: Cardiovascular Risk Factors and Noise Pollutionmentioning

confidence: 99%

“…Research has shown that environmental risk factors, including air pollutants, noise pollution, and the lack of green space, are independently associated with a higher risk of T2DM. 19 When these risk factors are considered together, they lead to a cumulative greater risk of T2DM. Access to more green spaces appears to be a crucial factor in mitigating these health risks.…”

Section: Strategies To Mitigate Noise Pollutionmentioning

confidence: 99%

Association of transportation noise with cardiovascular diseases

Shah,

Raj,

Kaur

et al. 2024

Clinical Cardiology

View full text Add to dashboard Cite

This comprehensive article delves into the intricate and multifaceted issue of noise pollution, shedding light on its diverse sources, profound health implications, and the economic burden it imposes on societies. Noise pollution is an increasingly prevalent environmental challenge, impacting millions of people worldwide, often without their full awareness of its adverse effects. Drawing from a wealth of scientific research, the article underscores the well‐established links between noise pollution and a spectrum of health issues, including cardiovascular diseases, sleep disturbances, and psychological stress. While exploring the sources and consequences of noise pollution, the article highlights the urgent need for a holistic and collaborative approach to mitigate its impact. This entails a combination of regulatory measures, technological innovations, urban planning strategies, and public education campaigns. It is increasingly evident that the detrimental effects of noise pollution extend beyond physical health, encompassing mental and social well‐being. The article also addresses the synergistic relationship between noise pollution and other environmental stressors, emphasizing the importance of considering noise in conjunction with factors like air pollution and access to green spaces. It examines the potential of green spaces to mitigate the effects of noise pollution and enhance overall health.

show abstract

Long-term exposure to transportation noise and risk of type 2 diabetes: A cohort study

Cited by 10 publications

References 24 publications

Transportation Noise Pollution and Cardiovascular Health

Transportation Noise Pollution and Cardiovascular Health

Health position paper and redox perspectives - Disease burden by transportation noise

Association of transportation noise with cardiovascular diseases

Contact Info

Product

Resources

About