Long‐Term Evaluation of<scp>ANKYLOS</scp>® Dental Implants, Part<scp>I</scp>: 20‐Year Life Table Analysis of a Longitudinal Study of More Than 12,500 Implants

Krebs, Mischa; Schmenger, Kai; Neumann, Konrad; Weigl, Paul; Moser, Walter; Nentwig, Georg-Hubertus

doi:10.1111/cid.12154

Cited by 72 publications

(95 citation statements)

References 27 publications

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“…Although the same evaluation as the primary efficacy endpoint (i.e., change in crestal bone level from baseline) was measured at 12 months, in retrospect, the change at 12 months should perhaps have been taken as a more clinically relevant primary efficacy endpoint. Increasingly, clinicians are calling for long-term evidence on dental implants and, as the time that implants have remained in situ in patients has increased over the years, more and more studies of 10, 15, and 20 years and over are being published and show high survival rates and low crestal bone loss [6, 65–71]. …”

Section: Discussionmentioning

confidence: 99%

A randomized, 12-month controlled trial to evaluate non-inferiority of early compared to conventional loading of modSLA implants in single tooth gaps

et al. 2016

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BackgroundThe aim of the study was to evaluate whether early loading of implants with a chemically modified sandblasted, large-grit, acid-etched (SLA) (SLActive®) surface was non-inferior to conventional loading in terms of change in crestal bone level.MethodsThis was a randomized, controlled, multicenter study. Patients requiring single-tooth rehabilitation in the posterior maxilla or mandible received implants and were randomized to receive a provisional restoration in occlusal load after 25 ± 3 days (early loading) or after 13 ± 1 weeks (conventional loading). The primary endpoint was change in crestal bone level between implant placement (baseline) and 6 months. Secondary endpoints included change in crestal bone level between baseline and 12 months, implant survival and success rates, and patient satisfaction.ResultsOf the 84 patients enrolled, 78 received implants and were randomized onto the early loading (41 patients) and conventional loading (37 patients) groups. The mean change in crestal bone level between baseline and 6 months was 0.56 ± 0.58 and 0.51 ± 0.62 mm for early and conventional loading, respectively; at 12 months, the mean change was 0.76 ± 0.60 and 0.73 ± 0.77 mm, respectively. Implant survival and success at 12 months were 100 % for both groups. Patient satisfaction was similar between the groups, except that more patients in the early loading group were satisfied or highly satisfied with the time taken for fitting.ConclusionThe study demonstrated that early implant loading was non-inferior to conventional implant loading in terms of crestal bone level change in a Japanese patient population in short follow-up period and single tooth gaps in molar regions.

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Section: Discussionmentioning

confidence: 99%

A randomized, 12-month controlled trial to evaluate non-inferiority of early compared to conventional loading of modSLA implants in single tooth gaps

et al. 2016

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“…While some studies reported reduced survival for implants in grafted areas [13, 14], other authors did not report any significant differences of implant survival or implant success between augmented and pristine bone [15, 16]. For sinus floor augmentation, Aghaloo et al even found favourable implant survival rates in augmented bone [17].…”

Section: Introductionmentioning

confidence: 99%

Retrospective analysis of 10,000 implants from insertion up to 20 years—analysis of implantations using augmentative procedures

Knöfler¹,

Barth²,

Graul³

et al. 2016

Int J Implant Dent

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BackgroundA sufficient amount of bone is essential to ensure long-term stability of dental implants. To support the bone regeneration process, different techniques and materials are available. It has been questioned whether these techniques and materials may compromise implant survival compared to pristine bone. To properly answer this question, long-term stability up to 20.2 years after insertion of implants placed in augmented or non-augmented sites was retrospectively analysed.MethodsRetrospective analysis included 10,158 implants from 3095 patients in three private practices who underwent implant therapy with or without bone augmentation procedures. Different graft materials and membranes were used for augmentation. If necessary, the graft was stabilised using a titanium mesh. Implant survival was evaluated analysing explantation rates and Kaplan-Meier survival curves in augmented or non-augmented sites. In additional subgroup analyses, augmentation procedures, graft materials and membranes were compared applying descriptive statistics.ResultsThe observation period varied from the day of implantation up to 20.2 years after implant insertion. The overall implant survival was 95.5% (augmented sites 96.33%; native sites 94.27%). Comparison of Kaplan-Meier survival curves revealed significantly better survival of implants in augmented sites (p = 0.0025). When comparing different augmentation procedures, the best results were found for bone condensing followed by lateral augmentation. Graft materials were used in 58.2%, membranes in 36.6% of all implant sites. The most often used graft materials were a deproteinized bovine bone mineral (53.0%) and autogenous bone particles (32.5%). Both provided the best results and showed a significantly better implant survival compared to no graft material using the Kaplan-Meier method (p = 0.0104 and p < 0.0001). A native collagen membrane was used most often (74.0% of the membrane sites) and provided the best results regarding implant survival in the log-rank test.ConclusionsThe retrospective analysis shows that implants inserted in augmented or native bone demonstrate similar implant survival under the conditions of private practice compared to prospective studies. To establish a broad base of support, further well-designed clinical trials are necessary.

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“…The use of dental implants for the treatment of edentulism has become increasingly popular, showing high rates of clinical success 1,2 . However, some factors limit the installation of dental implants, with bone availability being the most important local factor 3,4 .…”

Section: Introductionmentioning

confidence: 99%

Avaliação histomorfométrica da associação entre biovidro e osso bovino liofilizado no tratamento de defeitos ósseos críticos criados em calvárias de ratos. Estudo piloto

Spin

Oliveira

Spin‐Neto

et al. 2015

Rev. odontol. UNESP

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ResumoObjetivo: Avaliar histomorfometricamente o efeito de biovidro (B), osso bovino liofilizado (OB) ou da mistura desses dois biomateriais (B/OB -1:1) no reparo de defeitos ósseos críticos em calvária de ratos. Material e método: Defeitos ósseos (8 mm Ø) foram criados cirurgicamente na calvária de 24 ratos, distribuídos em 4 grupos com 6 animais, de acordo com o tipo de biomaterial: coágulo sanguíneo (GC), biovidro (GB), osso bovino liofilizado (GOB) e a mistura desses dois biomateriais (GB/OB). Os animais foram eutanasiados após 15 e 60 dias do procedimento cirúrgico (3 animais por período). A avaliação histológica foi baseada na descrição da morfologia dos tecidos neoformados, enquanto para a avaliação histomorfométrica foi realizada quantificação da porcentagem de tecido ósseo, de tecido conjuntivo fibroso neoformados e de biomaterial remanescente no defeito ósseo. Resultado: Nos dois períodos experimentais, a análise histológica apresentou neoformação óssea, principalmente nas bordas dos defeitos, e ao redor de partículas de biomateriais remanescentes. A avaliação histomorfométrica demonstrou que no período de 15 dias o grupo GC apresentou maior percentagem de tecido ósseo em relação aos demais grupos estudados, enquanto que aos 60 dias o grupo GOB apresentou maior porcentagem de tecido ósseo em relação ao grupo GB. Conclusão: O osso bovino liofilizado apresentou maior formação óssea em relação ao biovidro, mas nenhum dos biomateriais foi superior ao coágulo. A associação do biovidro e osso bovino liofilizado não adicionou vantagem à formação óssea.Descritores: Histologia; osso; reparo ósseo. AbstractObjective: This study sought to histomorphometrically evaluate the effect of bioglass (B), lyophilized bovine bone (BB) or the 1:1 mixture of these two biomaterials on the repair of critical bone defects in rat calvaria. Material and method: Bone defects (8 mm Ø) were surgically created in the calvaria of 24 rats, which were divided into the following 4 groups of 6 animals each according to the type of biomaterial used: blood clot / coagulum (control) group (CG), bioglass group (BG), lyophilized bovine bone group (BBG) and a group receiving a mixture of these two biomaterials (BG/BB). The animals were euthanized at 15 or 60 days after surgery (3 animals per period). Histological evaluation was based on the morphological description of the newly formed tissues, and a quantification of the percentage of bone tissue with newly formed fibrous connective tissue and the percentage of biomaterial remaining in the bone defect was performed for the histomorphometric evaluation. Result: In both experimental periods, the histological analysis showed new bone formation, especially at the edges of the defects and around remaining biomaterial particles. Histomorphometric analysis showed that the CG contained a higher percentage of bone tissue over the 15-day period compared to that of the other groups. At 60 days, the BBG showed a higher percentage of bone tissue compared to that of the BG (p <0.01). Conclusion: Lyophilized...

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Long‐Term Evaluation ofANKYLOS® Dental Implants, PartI: 20‐Year Life Table Analysis of a Longitudinal Study of More Than 12,500 Implants

Cited by 72 publications

References 27 publications

A randomized, 12-month controlled trial to evaluate non-inferiority of early compared to conventional loading of modSLA implants in single tooth gaps

A randomized, 12-month controlled trial to evaluate non-inferiority of early compared to conventional loading of modSLA implants in single tooth gaps

Retrospective analysis of 10,000 implants from insertion up to 20 years—analysis of implantations using augmentative procedures

Avaliação histomorfométrica da associação entre biovidro e osso bovino liofilizado no tratamento de defeitos ósseos críticos criados em calvárias de ratos. Estudo piloto

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