Long-Term Evaluation of Biocompatibility and Endurance of a Novel, Balloon Expandable Transcatheter Polymeric Aortic Valve in the Ovine Aortic Banding Model

6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model

“…Therefore in the current study we used a novel model of supra-aortic aortic banding prior to TAVI, which has been validated in large-series experiments. 8 , 9 This allowed us to anchor all implanted prostheses and perform a 6-month follow-up, albeit longer follow-up periods are possible. Contrary to previous reports, 11 in this model THV does not require any modification to anchor the prosthesis, thereby showing better resemblance to clinical setting.…”

“…Most recently, we introduced a novel ovine model of supra-aortic banding and THV implantation that allows for valve anchoring and long-term mechanical and biological evaluation, which is associated with significantly lower mortality when compared to previous models. 8 , 9 …”