Long-term environmental impact of arsenic-dispersion in Minas Gerais, Brazil

Matschullat, Jörg; Birmann, K.; Borba, Ricardo Perobelli; Ciminelli, Virgínia S. T.; Deschamps, Eleonora; Figueiredo, Bernardino Ribeiro; Gabrio, T.; Hassler, S. W.; Hilscher, A.; Junghänel, I.; Oliveira, N. de; Raßbach, K.; Schmidt, Hanka; Schwenk, Michael; Vilhena, M.J. de Oliveira; Weidner, U.

doi:10.1016/s1875-1121(06)09014-6

Cited by 6 publications

(4 citation statements)

References 12 publications

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“…To a lesser extent, As-based pesticides and wood preservation agents also contribute to Latin America’s water contamination (Bhattacharya et al, 2006; Bundschuh et al, 2004). Anthropogenic sources of As contamination are of concern in certain countries, including that from the mining and electric reefing industries in Brazil and As-containing pesticides in Mexico (Castro de Esparza, 2009a; Matschullat et al, 2007; Matschullat et al, 2000). …”

Section: History Occurrence Distribution and Exposed Population mentioning

confidence: 99%

“…Gold and copper mining have contributed to high levels of As in Brazil for over hundreds of years (Matschullat et al, 2007; Matschullat et al, 2000). Very high levels of As have been detected in the soil (50–1000 mg/kg) from the Iron Quardrangle area of the southeastern part of Brazil, where gold and other mining activities have been operating over 250 years (Matschullat et al, 2007).…”

Section: History Occurrence Distribution and Exposed Population mentioning

confidence: 99%

“…Very high levels of As have been detected in the soil (50–1000 mg/kg) from the Iron Quardrangle area of the southeastern part of Brazil, where gold and other mining activities have been operating over 250 years (Matschullat et al, 2007). Water from the mining districts Nova Lima and Santa Barbara contain As as high as 350 µg/L (Matschullat et al, 2007). …”

Section: History Occurrence Distribution and Exposed Population mentioning

confidence: 99%

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Arsenic exposure in Latin America: Biomarkers, risk assessments and related health effects

McClintock

Chen

Bundschuh

et al. 2012

Science of The Total Environment

157

106

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In Latin America, several regions have a long history of widespread arsenic (As) contamination from both natural and anthropological sources. Yet, relatively little is known about the extent of As exposure from drinking water and its related health consequences in these countries. It has been estimated that at least 4.5 million people in Latin America are chronically exposed to high levels of As (>50µg/L), some to as high as 2000 µg/L - 200 times higher than the World Health Organization (WHO) provisional standard for drinking water. We conducted a systematic review of 82 peer reviewed papers and reports to fully explore the current understanding of As exposure and its health effects, as well as the influence of genetic factors that modulate those effects in the populations of Latin America. Despite some methodological limitations, these studies suggested important links between high levels of chronic As exposure and elevated risks of numerous adverse health outcomes in Latin America - including internal and external cancers, reproductive outcomes, and childhood cognitive function. Several studies demonstrated genetic polymorphisms that influence susceptibility to these and other disease states through their modulation of As metabolism, with As methyltransferase (AS3MT), glutathione S-transferase (GST), and genes of one-carbon metabolism being specifically implicated. While the full extent and nature of the health burden are yet to be known in Latin America, these studies have significantly enriched knowledge of As toxicity and led to subsequent research. Targeted future studies will not only yield a better understanding of the public health impact of As in Latin America populations, but also allow for effective and timely mitigation efforts.

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Section: History Occurrence Distribution and Exposed Population mentioning

confidence: 99%

Section: History Occurrence Distribution and Exposed Population mentioning

confidence: 99%

Section: History Occurrence Distribution and Exposed Population mentioning

confidence: 99%

See 1 more Smart Citation

Arsenic exposure in Latin America: Biomarkers, risk assessments and related health effects

McClintock

Chen

Bundschuh

et al. 2012

Science of The Total Environment

157

106

View full text Add to dashboard Cite

show abstract

“…1), spontaneous urine was sampled from school children (mean age 9.8 AE 1.12 years) exposed to As from various sources. 18 Urine samples were immediately cooled after sampling (4 C) and frozen at À80 C until further processing. The samples were defrosted at room temperature.…”

Section: Instrumentationmentioning

confidence: 99%