Long-term efficacy of laparoscopic cholecystectomy for the treatment of biliary dyskinesia

Veenstra, Benjamin R.; Deal, Rebecca; Redondo, Raquel; Daly, Shaun; Najman, Jonathan; Myers, Jonathan A.; Millikan, Keith W.; Luu, Minh B.

doi:10.1016/j.amjsurg.2013.09.012

Cited by 15 publications

(11 citation statements)

References 7 publications

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“…from cholecystectomy even if they do not report complete resolution of symptoms. These results are consistent with previous pediatric studies noting postoperative symptom improvement in 79%e96% of patients [7e9,11e14] and adult studies reporting symptom improvement in >80% of patients on long-term follow-up [15]. From 2004e2010, the number of cholecystectomies performed for biliary dyskinesia rose by 63% [4].…”

Section: Discussionsupporting

confidence: 94%

Prediction of symptom improvement in children with biliary dyskinesia

Mahida¹,

Sulkowski²,

Cooper³

et al. 2015

Journal of Surgical Research

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Section: Discussionsupporting

confidence: 94%

Prediction of symptom improvement in children with biliary dyskinesia

Mahida¹,

Sulkowski²,

Cooper³

et al. 2015

Journal of Surgical Research

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“…Twenty‐one studies did not fulfil the inclusion criteria and were excluded. Twenty‐four studies 2,9–13,17,22–25,31,35–47 fulfilled the inclusion criteria (Fig. 1).…”

Section: Resultsmentioning

confidence: 99%

“…Presenting symptoms were classified as typical or atypical based on ROME II, III or IV criteria 8,15,16 . The majority of patients (1545, 90.4%) had typical symptoms, with 19 studies including only patients with typical symptoms 9–12,17,22–24,31,35–38,40,42–47 (Table 1). Four studies included those with typical or atypical symptoms, 165 (9.6%) patients having atypical symptoms 2,13,25,41 (Table 2).…”

Section: Resultsmentioning

confidence: 99%

“…The quality of non‐randomized studies was assessed using the Newcastle‐Ottawa Scale where a score of 9 is high quality 48 . Two studies scored 4, 22,47 four studies scored 5, 23,35,43,46 four studies scored 6, 9,10,17,40 seven studies scored 7, 25,36–38,41,42,44 five studies scored 8 2,11,13,31,45 and one study scored 9 24 . The sole RCT 12 was assessed using Jadad scoring system 33 which was 6 out of 8.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Cholescintigraphy may have a role in selecting patients with biliary dyskinesia for cholecystectomy: a systematic review

Alhayo

Eslick

Cox

2020

ANZ Journal of Surgery

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Background Patients with typical biliary pain, no gallstones on ultrasound and low gallbladder ejection fraction (GBEF) on cholescintigraphy (gallbladder dyskinesia) may be considered for a laparoscopic cholecystectomy. However, some studies have suggested that symptoms alone are an adequate indication for laparoscopic cholecystectomy. The aim was to determine the role of cholescintigraphy in predicting outcomes of cholecystectomy in patients with typical and atypical biliary symptoms and normal biliary ultrasound. Methods Meta‐analysis using Preferred Items for Systematic reviews and Meta‐Analysis (PRISMA) guidelines of published literature using several electronic databases. Results Twenty‐four articles were selected with a total of 1710 patients. The majority (n = 1633, 94.4%) of patients had typical biliary symptoms. A total of 1047 patients with typical symptoms and a reduced GBEF had a cholecystectomy with 852 (81.4%) having complete resolution of symptoms. A total of 148 with typical symptoms and normal GBEF had a cholecystectomy with 103 (69.5%) having complete resolution, which was significantly less than those with a reduced GBEF (odds ratio 1.65, confidence interval 1.08–2.05, P = 0.01). Forty‐five patients with atypical symptoms and a reduced GBEF had a cholecystectomy with 31 (68.9%) having complete resolution of symptoms, which is significantly lower than those with typical symptoms (odds ratio 1.97, confidence interval 0.95–3.90, P = 0.05). Conclusion Cholescintigraphy improved the predication of outcome of cholecystectomy in biliary dyskinesia by 10%. However, the presence of typical symptoms does predict an effective response in 70% of patients. Atypical symptoms predict a poorer response.

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“…In this context, the term biliary dyskinesia has historically been used as a general term that included both SO dyskinesia and gallbladder dyskinesia ( 26 ). Since the availability of scintigraphy, a functional gallbladder disorder (i.e., gallbladder dyskinesia/dysfunction) is now recognized as a discrete entity and should be distinguished from SO dyskinesia ( 27 – 29 ). The various forms of primary SOD are considered functional gastrointestinal disorders and may occur in adults or children of any age, but SOD is most commonly encountered in females aged 20–50 years ( 30 – 32 ).…”

Section: What Is Sod?mentioning

confidence: 99%

Sphincter of Oddi Function and Risk Factors for Dysfunction

Afghani

Covington³

et al. 2017

Front. Nutr.

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The sphincter of Oddi (SO) is a smooth muscle valve regulating the flow of biliary and pancreatic secretions into the duodenum, initially described in 1887 by the Italian anatomist, Ruggero Oddi. SO dysfunction (SOD) is a broad term referring to numerous biliary, pancreatic, and hepatic disorders resulting from spasms, strictures, and relaxation of this valve at inappropriate times. This review brings attention to various factors that may increase the risk of SOD, including but not limited to: cholecystectomy, opiates, and alcohol. Lack of proper recognition and treatment of SOD may be associated with clinical events, including pancreatitis and biliary symptoms with hepatic enzyme elevation. Pharmacologic and non-pharmacologic approaches are discussed to help recognize, prevent, and treat SOD. Future studies are needed to assess the treatment benefit of agents such as calcium-channel blockers, glyceryl trinitrate, or tricyclic antidepressants in patients with SOD.

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Long-term efficacy of laparoscopic cholecystectomy for the treatment of biliary dyskinesia

Cited by 15 publications

References 7 publications

Prediction of symptom improvement in children with biliary dyskinesia

Prediction of symptom improvement in children with biliary dyskinesia

Cholescintigraphy may have a role in selecting patients with biliary dyskinesia for cholecystectomy: a systematic review

Sphincter of Oddi Function and Risk Factors for Dysfunction

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