Long-Term Effects on Nipple Valve afterMassive Small Bowel Resection on Transit Time and Body Weight

Abstract

Four months after a 70% distal small bowel resection, transit time was decreased by 51.5 % in dogs with an intact ileocecal valve, 68.8% with a surgically constructed nipple valve, and 79.9% with a simple ileocecal anastomosis. Without an intact ileocecal valve, weight loss occurred. Stools were semiformed when a nipple valve or ileocecal valve was present, but liquid with a simple ileocecal anastomosis. This study suggests that the construction of a nipple valve may prevent some complications related to the loss of the ileocecal valve and massive small bowel resection.

Valvular Colonic Sphincter Substitutes

“…Therefore, it may be related to reorgani zation of the smooth muscle actin-myosin filaments, as has been suggested by Holschneider et al [ 11 ]. It is interesting to note in this context that the effects of ileocecal sphincter substitution on intestinal transit and weight loss also decreased after some months [ 15]. As pressure values up to 90 mm Hg could be installed but not maintained by calibrating valves, we cannot believe that it would be possible to construct a higher pres sure zone using colon smooth muscle coats without causing fibrosis.…”