Long-term effects of home-based pulmonary rehabilitation on idiopathic interstitial pneumonia patients

Abstract

Currently, interstitial lung disease (ILD) has no unified treatment plan. Home-based pulmonary rehabilitation (PR), as a non-pharmacological treatment, is a non-invasive and low-cost option for improving exercise capacity and quality of life. This study explores the impact of home-based PR on lung function, and the quality of life of patients with ILD. In this randomized prospective study, 60 patients with ILD were randomly assigned to the home-based PR intervention and traditional drug treatment groups, and they were followed for 12 months. The outcome measures were the 6-min walk distance (6MWD), exercise-related dyspnea, and St George's Respiratory Questionnaire score (SGRQ). It found that the 6MWD results were significantly improved from 348.5 ± 106.1 m at baseline to 403.6 ± 100.3 m on the completion of PR and 443.8 ± 96.5 at 1-year follow-up (P = 0.001). Compared with the control group, the home-based PR group had slightly improved pulmonary function. Furthermore, the severity of dyspnea evaluated with mMRC in the home-based PR group improved from 2.9 ± 1.1 at baseline to 2.2 ± 0.9 after the home-based PR program, and this improvement persisted after 12 months (P = 0.001). Additionally, home-based PR for patients with ILD improved the functional pulmonary performance and the SGRQ score results.

The effects of telerehabilitation on physiological function and disease symptom for patients with chronic respiratory disease: a systematic review and meta-analysis

“…The intervention effect of telerehabilitation on CRD was reported in 8 [ 14 , 15 , 21 , 4 , 23 – 25 , 28 ] studies using mMRC, comprising 497 participants in the experimental group and 587 participants in the control group. Employing a fixed-effects model ( I 2 = 2%, P = 0.43) for effect size pooling, the analysis revealed that compared to conventional rehabilitation in the control group, telerehabilitation in the experimental group showed significant improvement in outcomes both at ≤ 6 months post-intervention [WMD = -0.29, 95%CI (-0.41, -0.18)] and > 6 months [WMD = -0.38, 95%CI (-0.56, -0.21)].…”

“…Subgroup analysis of Pulmonary function was conducted based on FEV1% predicted and FEV1/FVC (%). In 3 [ 17 , 23 , 33 ] studies reporting FEV1% predicted, the intervention effects of telerehabilitation on CRD were examined, with 127 participants in the intervention group and 107 participants in the control group. Employing a fixed-effects model ( I 2 = 51%, P = 0.13) for effect size pooling, the analysis results showed that there was no statistically significant difference between the intervention and control groups in terms of FEV1% predicted [WMD = 2.19, 95%CI (-0.55, 4.93)] (See Fig.…”