Long-term effects of a reduced fat diet intervention on cardiovascular disease risk factors in individuals with glucose intolerance

Ley, Sarah; Metcalf, Patricia; Scragg, Robert; Swinburn, Boyd

doi:10.1016/j.diabres.2003.09.001

Cited by 36 publications

(23 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Meanwhile waist circumference is able to provide an estimate of abdominal fat, which in turn is correlated with the amount of intra-abdominal adipose tissue 4,16,25,26 . Weight changes are also known to relate to age; individuals who gain more than 10% weight from the age of 20 until middle age significantly increase their odds of developing arterial hypertension, dyslipidemia, and hyperinsulinemia 11,27 .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

All-cause mortality among Japanese-Brazilians according to nutritional characteristics

2007

View full text Add to dashboard Cite

The aim of this study was to verify the association between nutritional variables and mortality in a Japanese-Brazilian cohort. In 1993, 647 subjects were interviewed with food frequency questionnaires and scheduled for physical procedures (weight, height, blood pressure) and biochemical tests (oral glucose tolerance test). Student's t test was used to compare the mean values of target variables between living and deceased subjects. Mortality rate and hazard ratios were obtained (crude and adjusted) according to the nutritional variables. Overall mortality rates were 21.4 and 11.7/1,000 person-years for males and females, respectively. Smoking, diabetes, sedentary lifestyle, hypertension, higher mean age, high blood pressure, high blood glucose, and higher percent weight gain and rate of weight gain were observed in the history of deceased subjects. After adjusting for control variables, an increase was observed in mortality among individuals with lower carbohydrate and cholesterol intake. The results suggest that mortality risk factors like age, chronic diseases, sedentary lifestyle, smoking, and inadequate diet must also be acting in the Japanese-Brazilian population.

show abstract

Section: Introductionmentioning

confidence: 99%

“…High intake of saturated fat can induce insulin resistance and thus worsen blood glucose control 10,11 .…”

Section: Introductionmentioning

confidence: 99%

All-cause mortality among Japanese-Brazilians according to nutritional characteristics

2007

View full text Add to dashboard Cite

show abstract

“…Fourteen randomised controlled trials were identified that presented evidence on diets differing in the proportion of carbohydrate to fat on systolic and diastolic blood pressure, all of which were included in the meta-analysis (Golay et al, 2000;Foster et al, 2003;Lovejoy et al, 2003;Clifton et al, 2004;Ley et al, 2004;Dansinger et al, 2005;Ebbeling et al, 2005;Howard et al, 2006b;Ebbeling et al, 2007;Gardner et al, 2007;Maki et al, 2007b;Phillips et al, 2008;Frisch et al, 2009;Sacks et al, 2009). Six trials were subsequently identified in the update search Gulseth et al, 2010;Jebb et al, 2010;Howard et al, 2010;Tierney et al, 2011;Brooking et al, 2012) (Cardio-metabolic review, incident hypertension and blood pressure chapter p 49, 53; Update search table 47).…”

Section: Vascular Functionmentioning

confidence: 99%

“…Nineteen randomised controlled trials that presented evidence on diets differing in the proportion of carbohydrate to fat on fasting total cholesterol were included in the metaanalysis (Campos et al, 1995;Nelson et al, 1995;Ginsberg et al, 1998;Turley et al, 1998;Zambon et al, 1999;Golay et al, 2000;Colette et al, 2003;Couture et al, 2003;Lovejoy et al, 2003;Clifton et al, 2004;Ley et al, 2004;Pelkman et al, 2004;SegalIsaacson et al, 2004;Cornier et al, 2005;Lofgren et al, 2005;Petersen et al, 2006;Howard et al, 2006b;Due et al, 2008b;Frisch et al, 2009). Five trials were subsequently identified in the update search Howard et al, 2010;Haufe et al, 2011;Tierney et al, 2011;Brooking et al, 2012) (Cardio-metabolic review, the hyperlipidaemias and blood lipids chapter p 65-72; Update search table 62).…”

Section: 30mentioning

confidence: 99%

“…a concomitant reduction in saturated fat intake and/or weight loss  The effect is biologically relevant Fasting HDL-cholesterol 5.36. Twenty two randomised controlled trials that presented evidence on diets differing in the proportion of carbohydrate to fat on fasting HDL-cholesterol were included in the metaanalysis (Campos et al, 1995;Nelson et al, 1995;Ginsberg et al, 1998;Turley et al, 1998;Zambon et al, 1999;Golay et al, 2000;Wolever & Mehling, 2002;Foster et al, 2003;Colette et al, 2003;Couture et al, 2003;Lovejoy et al, 2003;Clifton et al, 2004;Ley et al, 2004;Pelkman et al, 2004;Segal-Isaacson et al, 2004;Cornier et al, 2005;Bhargava, 2006;Petersen et al, 2006;Howard et al, 2006b;Ebbeling et al, 2007;Due et al, 2008b;Frisch et al, 2009). Seven trials were subsequently identified in the update search Howard et al, 2010;Foster et al, 2010;Haufe et al, 2011;Tierney et al, 2011;de Souza et al, 2012;Brooking et al, 2012) Of the trials identified in the update search, four report no significant effect of diets differing in the proportion of carbohydrate and fat on fasting HDL-cholesterol concentration (Howard et al, 2010;Haufe et al, 2011;de Souza et al, 2012;Brooking et al, 2012).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Macronutrients and type 1 diabetes (revision number 6)

Garden¹,

Paterson²

2014

Diapedia

View full text Add to dashboard Cite

Long-term Effects of a Lifestyle Intervention on Weight and Cardiovascular Risk Factors in Individuals With Type 2 Diabetes Mellitus

2010

Arch Intern Med

742

444

View full text Add to dashboard Cite

Objective Lifestyle interventions produce short-term improvements in glycemia and cardiovascular disease (CVD) risk factors in individuals with type 2 diabetes, but no long-term data are available. We examined the effects of a lifestyle intervention on changes in weight, fitness and cardiovascular (CVD) risk factors over 4 years. Research Design and Methods Look AHEAD is a multi-center randomized clinical trial comparing the effects of intensive lifestyle intervention (ILI) and diabetes support and education (DSE, control group) on the incidence of major CVD events in 5145 individuals with type diabetes, aged 45 to 76 years, who were overweight or obese (BMI > 25 kg/m2). Participants have ongoing intervention and annual assessments. Results Averaged across four years of follow-up, participants in ILI had greater percent weight losses than those in DSE (−6.15% vs −0.88%, p<.0001) and greater improvements in fitness (12.74% vs. 1.96%, p < .0001), HbA1c (A1c, −0.36% vs. 0.09%, p<.0001), systolic blood pressure (SBP, −5.33 vs. −2.97 mmHg, p<.0001), diastolic blood pressure (DBP, −2.92 vs. −2.48 mmHg, p<.012), HDL-cholesterol (HDL-C, 3.67 vs. 1.97 mg/dl, p<.0001), and triglycerides (−25.56 vs. −19.75 mg/dl, p<.0006). Reductions in LDL-C were greater in DSE than ILI (−11.27 vs. −12.84 mg/dl, p=.009), but adjusted for medication use, changes in LDL-C did not differ between the two groups. Although the greatest benefits were often seen at 1 year, ILI participants still had greater improvements than DSE in weight, fitness, HbA1c, SBP, and HDL-C at 4 years. Conclusions Intensive lifestyle intervention can produce and maintain significant weight losses and improvements in fitness in individuals with type 2 diabetes. Across four years of follow-up, those in ILI had better overall levels of glycemic control, blood pressure, HDL-C and triglycerides, and thus spent considerable time with lower CVD risk. Whether this translates to reduction in CVD events will ultimately be addressed by the Look AHEAD study.

show abstract

Long-term effects of a reduced fat diet intervention on cardiovascular disease risk factors in individuals with glucose intolerance

Cited by 36 publications

References 34 publications

All-cause mortality among Japanese-Brazilians according to nutritional characteristics

All-cause mortality among Japanese-Brazilians according to nutritional characteristics

Macronutrients and type 1 diabetes (revision number 6)

Long-term Effects of a Lifestyle Intervention on Weight and Cardiovascular Risk Factors in Individuals With Type 2 Diabetes Mellitus

Contact Info

Product

Resources

About