“…The participants in the included studies were adult patients aged ≥18 years with a range of diseases: various cancers [ 53 , 63 , 65 , 66 , 69 , 70 , 73 , 75 - 77 ], along with cardiovascular [ 54 , 56 - 58 , 64 , 68 , 71 , 72 , 74 ], musculoskeletal [ 59 , 62 ], colorectal [ 55 , 60 , 61 ], and kidney diseases [ 78 ]. The sample size ranged from 29 to 1000 patients, with, of the 26 studies, 9 (35%) having enrolled fewer than 99 participants [ 58 - 60 , 62 , 64 , 68 , 73 , 76 , 78 ], 9 (35%) having enrolled 100-200 participants [ 53 , 54 , 61 , 66 , 69 , 70 , 74 , 75 , 77 ], 7 (27%) having enrolled 201-500 participants [ 55 - 57 , 63 , 65 , 67 , 72 ], and 1 (4%) having enrolled 1000 participants [ 71 ].…”