Long‐term effectiveness and persistence rate of ustekinumab dose intensification in a South East Asian inflammatory bowel disease center
Chong‐Teik Lim,
Shu‐Wen Tay,
Sakktivel Elangovan
et al.
Abstract:Background and AimsUstekinumab (UST) is an effective biologic for treatment of inflammatory bowel disease (IBD). However, some patients treated with UST have suboptimal clinical response with standard dosing. The aims of this study were to determine the effectiveness of UST dose intensification (DI), identify factors associated with DI, cumulative incidence of DI and persistence of UST among treated patients.MethodsClinical data of patients with Crohn's disease (CD) and ulcerative colitis (UC) who received UST… Show more
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