Long term effect of phacoemulsification on intraocular pressure in patients with medically controlled primary open-angle glaucoma

Majstruk, Loic; Leray, B; Bouillot, A.; Michée, Sylvain; Sultan, G.; Baudouin, Christophe; Labbé, Antoine

doi:10.1186/s12886-019-1157-3

Cited by 44 publications

(38 citation statements)

References 34 publications

(40 reference statements)

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“…Previous studies showed 6-26% of patients had increase in postoperative IOP and 4-26% of patients needed increase in IOP-lowering medication at 1-5 years following phacoemulsification [23][24][25][26][27][28]. In this present study we found 17% OAG eyes with a postoperative IOP increase…”

Section: Plos Onesupporting

confidence: 60%

“…Chen et al demonstrated 13% IOP reduction in eyes with primary open angle glaucoma (POAG) following phacoemulsification alone [23]. But other reports revealed considerable variability of outcomes with postoperative IOP reduction ranging from 7 to 22% [24,25]. The different study designs and the variability of inclusion and exclusion criteria may account for this.…”

Section: Plos Onementioning

confidence: 99%

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Outcome of phacoemulsification in patients with open-angle glaucoma after selective laser trabeculoplasty

Park

Cho

2020

PLoS ONE

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To investigate the outcome of phacoemulsification in selective laser trabeculoplasty (SLT)treated eyes. Methods This retrospective study included patients who had open angle glaucoma (OAG) with previous SLT who underwent phacoemulsification. We evaluated intraocular pressure (IOP), length of glaucoma control without treatment, and antiglaucoma medication or surgery. SLT-treated eyes that did not receive phacoemulsification were retrospectively chosen as a control. We investigated factors related to outcome of phacoemulsification by multivariate analysis. Results 42 eyes with previous SLT that underwent phacoemulsification and 40 controls were retrospectively evaluated. Phacoemulsification was performed 52 ± 15 months after SLT. After a mean follow-up of 74 ± 21 months, mean IOP was significantly decreased in the phaco group by 2.2 ± 2.7 mmHg (p < 0.001). In the SLT group, mean IOP was decreased by 0.8 ± 2.8 mmHg (p < 0.001). 9 eyes (16.7%) in the phaco group and 11 eyes (19.0%) of the SLT group needed topical treatment, and no eye needed glaucoma surgery in both groups. The factor related to success was higher baseline IOP (p = 0.002). Conclusion Prior SLT didn't negatively influence phacoemulsification in patients with OAG. Phacoemulsification lowered IOP effectively and safely in OAG patients who were treated with SLT.

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Section: Plos Onesupporting

confidence: 60%

Section: Plos Onementioning

confidence: 99%

Outcome of phacoemulsification in patients with open-angle glaucoma after selective laser trabeculoplasty

Park

Cho

2020

PLoS ONE

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“…The small discrepancy between the studies can probably be attributed, among other factors, to different mean baseline IOP values. In patients with POAG, similar analyses of long-term effects showed a slightly different IOP reduction one year after the procedure: by 1.15 ±3 mmHg (6.8 ±18.1%) [17], by 1.0 ±5.5 [12], or by 13% [18]. A large metaanalysis found that the mean reduction in IOP noted at 6, 12, 24 and 36 months after the surgery was 12%, 14%, 15% and 9% from the baseline, respectively [14].…”

Section: Discussionmentioning

confidence: 81%

“…In a recently published paper, a decrease in the number of medications was achieved in 17.1% of patients. A total of 7.2% patients required additional glaucoma medications, and in 75.7% of patients with POAG the number of medications remained unchanged [17]. Reducing the dependence on glaucoma medications limits their adverse effects on the ocular surface [14], leading to improved patient comfort and potentially increasing therapeutic compliance.…”

Section: Discussionmentioning

confidence: 99%

Ab interno goniotomy with a Kahook Dual Blade in 6-month follow-up

Majer¹,

Kaszuba-Modrzejewska²,

Petrus³

et al. 2020

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Aim of the study: Evaluation of ab interno goniotomy using a Kahook Dual Blade in combination with phacoemulsification in patients with primary open angle glaucoma during a 6-month follow-up. Material and methods: 75 patients with mild and moderately advanced primary open angle glaucoma, who had phacoemulsification combined with ab interno goniotomy using a Kahook Dual Blade (New World Medical, USA), were included in this analysis. The average age was 68.4 ±8.9 years. Mean pre-and postoperative intraocular pressure, number of antiglaucoma medications, complications of the surgery and need for another procedure were analysed in the 6-month follow-up. Results: Before the surgery, mean intraocular pressure was 21.9 ±3.9 mmHg and the number of antiglaucoma medications was 2.2 ±1.2. A reduction in intraocular pressure of 17.53% and a decrease in number of antiglaucoma medications of 60% (p < 0.001) were observed in the 6-month follow-up. There was slight intra-operative bleeding into the anterior chamber from the incision in all cases. On the first days after surgery there were diffuse blood cells or a clot in the anterior chamber in 38% of eyes. Increase in intraocular pressure above 25 mmHg on the first day after surgery was observed in 30.6% of eyes. In one eye there was no postoperative intraocular pressure stabilisation and laser cyclodestruction was performed. Conclusions: Ab interno goniotomy performed simultaneously with phacoemulsification results in a significant reduction in intraocular pressure and a decrease in the number of anti-glaucoma drugs used. The treatment is characterized by a good safety profile and does not require intensive postoperative management.

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“…A sizeable proportion of medically controlled glaucoma patients with open angles undergoing phacoemulsification experienced a rise in IOP or required more aggressive treatment to regulate IOP postoperatively. 13,14 In contrast to this, our study did not take into account the pre-operative medical treatment of glaucoma into consideration.…”

Section: Discusionmentioning

confidence: 99%

Effect of Cataract Surgery on Intraocular Pressure in Glaucoma Patients

Azam

Talpur²,

Shaheen³

et al. 2020

pak J Ophthalmol

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Purpose: To determine the change in intraocular pressure after cataract surgery in patients diagnosed with glaucoma. Study Design: Interventional case series. Place and Duration of Study: Glaucoma Clinic. Al-Ibrahim Eye Hospital (AIEH) Karachi, Pakistan from May to October, 2019. Methods: Thirty-eight patients diagnosed with glaucoma and cataract and registered in glaucoma clinic were recruited for this study. Inclusion Criteria was age > 41 years and patients diagnosed with primary open/closed angle glaucoma and cataract. Patients with secondary glaucoma, history of trabeculectomy and any other ocular diseases were excluded from the study. Pre-operative assessment was done for phacoemulsification. In post-operative examination, first and second follow-up IOP was measured. Data analysis was done on statistical package for social science (SPSS) version 20.0. Statistical changes were present in the form of bar chart, frequency and graphs. The mean standard deviation for pre-operative, post-operative 1st and 2nd follow-up IOP was calculated. Results: A total of 38 participants and 48 eyes satisfied the inclusion criteria. Out of 48 eyes, 39 (81.3%) eyes were diagnosed with Primary open angle glaucoma and 9 (18.8%) eyes with Primary Angle Closure Glaucoma. The pre-operative mean IOP was 16.56 ± 6.67 mm Hg and post-operative mean IOP at first follow-up was 13.39 ± 4.04 mm Hg. At second follow-up at one-month mean IOP was 12.14 ± 2.28 mm Hg. Conclusion: Phacoemulsification produces a useful decrease in IOP in glaucoma patients. Key Word: Glaucoma, Cataract, Phacoemulsification, Intraocular Pressure.

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Long term effect of phacoemulsification on intraocular pressure in patients with medically controlled primary open-angle glaucoma

Cited by 44 publications

References 34 publications

Outcome of phacoemulsification in patients with open-angle glaucoma after selective laser trabeculoplasty

Outcome of phacoemulsification in patients with open-angle glaucoma after selective laser trabeculoplasty

Ab interno goniotomy with a Kahook Dual Blade in 6-month follow-up

Effect of Cataract Surgery on Intraocular Pressure in Glaucoma Patients

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