Long-Term Effect of Ileogastrostomy Surgery for Morbid Obesity on Diabetes Mellitus and Sleep Apnea

Abstract

This is the first report of the long-term effect of the ileogastrostomy on diabetes mellitus and sleep apnea. The ileogastrostomy was associated with rapid improvement or normalization of diabetes mellitus, similar to the biliopancreatic diversion and the Roux-en-Y gastric bypass, but faster than other bariatric operations. Improvement in sleep apnea was slower and was related to weight loss, similar to other bariatric operations.

Sleep Apnea and Cardiovascular Disease

“…The most dramatic results have been reported with surgical weight loss. [312][313][314] In addition, apnea often is worse in the supine posture, with some patients having OSA only in that position. 315,316 For patients with "positional apnea," behavioral techniques aimed at keeping the patient in the lateral posture during sleep (an uncomfortable object sewn into the back of the nightshirt or positional alarms) may offer benefit.…”

Sleep Apnea and Cardiovascular Disease

“…Weight loss can lead to a decrease in AHI, improved sleep efficiency, decreased snoring, and improved oxygenation. The most dramatic results have been reported with surgical weight loss (312)(313)(314). In addition, apnea often is worse in the supine posture, with some patients having OSA only in that position (315,316).…”

Obesity, obstructive sleep apnea and type 2 diabetes mellitus: Epidemiology and pathophysiologic insights

“…Obesity is increasing globally and the associated diseases, OSA and T2DM prevalence is also increasing globally. 80,81 OSA and T2DM are common findings in patients. 82 OSA is a risk factor for T2DM, metabolic syndrome and cardiovascular diseases.…”

“…82 OSA is a risk factor for T2DM, metabolic syndrome and cardiovascular diseases. 80,81 One more Cohort study shows moderate to severe OSA is one of the major risk factor in causing incidental T2DM. 83 Moderate to severe OSA increases blood sugar level in T2DM patients, because hypoxemia triggers hyperglycaemia in patients with T2DM along with OSA.…”