Long-term durability of a new surgical aortic valve: A 1 billion cycle in vitro study

Sadri, Vahid; Trusty, Phillip M.; Madukauwa-David, Immanuel David; Yoganathan, Ajit P.

doi:10.1016/j.xjon.2021.10.056

Cited by 9 publications

(3 citation statements)

References 17 publications

(26 reference statements)

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“…18 Sadri et al tested the durability of this valve in vitro and determined that it withstood up to 25 years of wear. 19 Additional follow-up will be necessary to determine long-term outcomes in vivo. An important consideration in patients implanted with bioprosthetic valves is the possibility of patient-prosthesis mismatch (PPM), a complication that occurs when the implanted valve is too small, causing an excessive gradient across the valve and inadequate cardiac output.…”

Section: Bioprosthetic Valvesmentioning

confidence: 99%

Partial Heart Transplantation in Adult Cardiac Surgery

Sherard

Bisbee

Konsek

et al. 2023

Innovations�(Phila)

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Many young adults require heart valve replacements. Current options for valve replacement in adults include mechanical valves, bioprosthetic valves, or the Ross procedure. Of these, mechanical and bioprosthetic valves are the most common options, although mechanical valve usage predominates in younger adults due to durability, while bioprosthetic valve usage predominates in older adults. Partial heart transplantation is a new method of valvular replacement that can deliver durable and self-repairing valves and allow adult patients freedom from anticoagulation therapy. This procedure involves transplantation of donor heart valves only, permitting expanded utilization of donor hearts as compared with orthotopic heart transplantation. In this review, we discuss the potential benefits of this procedure in adults who elect against the anticoagulation regimen required of mechanical valve replacements, although it has not yet been clinically established. Partial heart transplantation is a promising new therapy for the treatment of pediatric valvular dysfunction. This is a novel technique in the adult population with potential utility for valve replacement in young patients for whom anticoagulation therapy is problematic, such as women who wish to become pregnant, patients with bleeding disorders, and patients with active lifestyles.

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Section: Bioprosthetic Valvesmentioning

confidence: 99%

Partial Heart Transplantation in Adult Cardiac Surgery

Sherard

Bisbee

Konsek

et al. 2023

Innovations�(Phila)

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show abstract

“…Since the recently developed RESILIA INSPIRIS valve (Edwards Lifesciences, Irvine, Calif) has potential long-lasting durability, Sadri and colleagues' simulation study is timely and essential. 4 They performed an in vitro accelerated wear study, evaluated hemodynamic and leaflet kinematic profiles, and examined fluid flow with particle image velocimetry following one billion cycles. This allowed close examination of some of the critical factors affecting BPV durability.…”

mentioning

confidence: 99%

Commentary: Lasting durable bioprosthetic valves: Truth or fiction

Alnajar¹,

Ibrahim²,

Elgalad³

et al. 2022

JTCVS Open

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“…In the current issue of the Journal , Sadri and colleagues 2 evaluate the anatomical and hemodynamic modifications of the aortic valve INSPIRIS RESILIA (Edwards Lifesciences, Irvine, Calif) after long-term use, using accelerated wear tests. In their paper, the authors compared effective orifice areas and flow characteristics of three 21-mm and 23-mm INSPIRIS RESILIA valves with their respective values at zero cycle conditions.…”

mentioning

confidence: 99%