Long-term complications of renal transplantation

We, Braun

doi:10.1038/ki.1990.123

Cited by 103 publications

(36 citation statements)

References 101 publications

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“…The lower mortality in transplant patients is related to factors such as selection of patients at a lower risk for transplantation and risk reduction resulting from the transplantation itself. It is important to observe that despite the lower mortality of transplant patients when compared to that of patients undergoing dialysis, cardiovascular diseases remain the main cause of death [1][2][3][4][5] .…”

Section: Introductionmentioning

confidence: 99%

Evolução clínica pós-stent coronariano em pacientes submetidos a transplante de rim

Mota¹,

Araújo²,

Arruda³

et al. 2007

Arq. Bras. Cardiol.

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SummaryObjective: To assess the clinical outcome of renal transplant patients who developed coronary artery disease and were treated with coronary stenting (TCA-ST). Methods:Hospital do Rim e Hipertensão medical visits and phone calls. Results:drug-eluting stents.Conclusion: In conclusion, renal transplant patients who developed CAD and were treated with coronary stenting had a low rate of in-stent restenosis, probably related to the immunosuppressive regimen given to prevent kidney rejection.

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Section: Introductionmentioning

confidence: 99%

Evolução clínica pós-stent coronariano em pacientes submetidos a transplante de rim

Mota¹,

Araújo²,

Arruda³

et al. 2007

Arq. Bras. Cardiol.

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“…Sin embargo, en los últimos años estamos asistiendo a un aumento en el número de aislamientos de otras especies (con una mayor resistencia a antifún-gicos). La infección por hongos del género Aspergillus constituye una de las principales causas de muerte en los pacientes con TPH 6 . La mayoría de estas infecciones están causadas por A. fumigatus, mientras que A. flavus y A. niger son especies menos frecuentes.…”

Section: Infecciones Fúngicasunclassified

Infecciones más comunes en el paciente trasplantado

Yuste

Pozo

Quetglas

et al. 2006

Anales Sis San Navarra

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Organ transplantation has become one of the most important areas of medical research and, at present, is still the only therapeutical tool for several diseases. However, there are a number of factors related to transplantation, like immunosuppression and prolonged neutropenia that affect the incidence of infection. These infections are somehow peculiar to trasplant recipients. In fact, there are infectious diseases that only occur in immunodepression situations and, moreover, clinical expression of these infectious diseases can be quite different from that in immunocompetent patients. Besides these aspects, some infections, due to the high prevalence described, must be considered for prevention strategies because they continue to be a principal cause of morbidity and mortality, either due to direct effects or to their implication in the pathogenesis of rejection. These strategies commence before trasplantation by active immunization through vaccine administration to the patient and to people in the milieu and continue after trasplantation with prophylaxis or pre-emptive therapy. The importance of infectious diseases in the evolution and prognosis of trasplant recipients gives a special meaning to the understanding of associated infections, their clinical expression and ways of prevention and treatment.

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“…The diet should contain complex carbohydrates (50-60% of total calories) and [20][21][22][23][24][25][26][27][28][29][30] 39 Hyperlipidaemia risk profiles should be identified by regular screening (at least once a year) for cholesterol, HDL-cholesterol, LDLcholesterol, triglyceride blood levels in renal transplant patients.…”

Section: What Do the Other Guidelines Say?mentioning

confidence: 99%

Nutritional management of dyslipidaemia in adult kidney transplant recipients

Chadban¹,

Chan²,

Fry³

et al. 2010

Nephrology

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Once graft is functioning:• A diet rich in wholegrain, low glycaemic index and high fibre carbohydrates as well as rich sources of vitamin E and monounsaturated fat should be recommended to adult kidney transplant recipients with elevated serum total cholesterol, LDL-cholesterol and triglycerides. (Level III-IV) • Weight reduction in overweight or obese kidney transplant recipients should be encouraged and supported. (Level IV) (Refer to CARI Guideline: Nutritional management of overweight and obesity in adult kidney transplant patients)• Kidney transplant recipients with dyslipidaemia should be advised to eat a diet which reflects the evidence described above while being in line with lipid management guidelines for the general population as follows:1 Carbohydrate Carbohydrate should be consumed predominantly in the form of wholegrains and foods with a low energy density and/or low glycaemic index, aiming for a daily fibre intake of 25 g for females and 30 g for males. The inclusion of the soluble fibre beta-glucan should be encouraged as it has been shown to lower LDLcholesterol in non-transplant populations. 1-4 2 FatTotal fat should contribute 30-35% of total energy intake. Saturated and trans fatty acids together should contribute no more than 8% of total energy intake. n-6 polyunsaturated fat should contribute 8-10% of total energy. Monounsaturated fat may contribute up to 20% of total energy intake. n-3 polyunsaturated fat should be included in the diet as both plant and marine sources. 6,7• Alcohol should be limited to no more than two standard drinks on any day for both men and women. This advice is based on NHMRC guidelines for lifetime health risks associated with daily alcohol consumption by 'healthy' men and women. 8 The potential direct effect of alcohol consumption on serum lipids, as well as the energy yield of alcohol (29 kilojoules per gram) and the contribution it may make to excessive energy intake and weight gain, should also be considered. BACKGROUNDDyslipidaemia is common after renal transplantation, estimated to be present in around 60% of kidney transplant recipients. The definition of dyslipidaemia which has been adopted by the National Kidney Foundation KDOQI, 10 based on that of the Adult Treatment Panel III, 11 is the presence of one or more of the following: total serum cholesterol >200 mg/dL; LDL-cholesterol >130 mg/dL; triglycerides >150 mg/dL; HDL-cholesterol <40 mg/dL. The typical lipid profile of transplant recipients includes elevated total serum cholesterol and low-density lipoprotein cholesterol (LDL-C), with variable high-density lipoprotein cholesterol (HDL-C) and triglycerides. [12][13][14][15] Studies have shown that lipoprotein abnormalities are a persistent problem even 10 years post-transplant. 16,17 The correlation between dyslipidaemia and cardiovascular disease (CVD) risk in non-transplant populations has been well established.11 Several studies have reported a positive association between total cholesterol and atherosclerotic CVD in kidney transplant recipients, si...

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Long-term complications of renal transplantation

Cited by 103 publications

References 101 publications

Evolução clínica pós-stent coronariano em pacientes submetidos a transplante de rim

Evolução clínica pós-stent coronariano em pacientes submetidos a transplante de rim

Infecciones más comunes en el paciente trasplantado

Nutritional management of dyslipidaemia in adult kidney transplant recipients

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