Long term clinical performance of 10 871 dental implants with up to 22 years of follow‐up: A cohort study in 4247 patients

Abstract

Background The present retrospective study was aimed to assess the long‐term clinical performance of dental implants in a cohort study of 4247 patients. Methods A longitudinal observational cohort study was done on all implants performed by a single periodontist from July 1995 to April 2019. The main outcome variables of this study were implant failure and marginal bone level around implants. Results The study participants received a total of 10 871 implants with a mean of 2.56 implants per patient. The cohort was followed‐up to 22.2 years (mean = 4.5 ± 4.2). Among the 4247 patients of the current study, 140 patients (3.3%) experienced a combined total of 178 implant failures. According to life table analysis, at the implant level the cumulative survival rate at 3, 5, 10, and 15 years was 98.9%, 98.5%, 96.8%, and 94.0%, respectively while at patient level was 97.4%, 96.7%, 92.5%, and 86% at 3, 5, 10, and 15 years. Patients with multiple units were at a greater risk for having an implant failure. Baseline bone level was 0.09 ± 0.28 mm while at 8–10 years the mean bone level was 0.49 ± 0.74 mm. The incidence of peri‐implant mucositis at the implant level was 9.4% at 2–3 years, 9.3% at 4–5 years, 12.1% at 6–7 years, and 11.9% at 8–10 years. The incidence of peri‐implantitis was 2%, 2.6%, 3.2%, and 7.1% at 2–3, 4–5, 6–7, and 8–10 years, respectively. Cigarette smoking and diabetes mellitus were positively correlated with implant failure. Conclusions Though the results are promising and encouraging in terms of survival and bone level over time, it is important to emphasize the potential risk factors and consider them prior to dental implant placement.

Stability of Implants Supported By Three Types of Bone Grafting Materials in Dogs

“…The structure of sternum resembles the upper jaw. The failure rate of implants was calculated as 17% in this study, which is higher than that reported in usual conditions (11)(12)(13). However, it has been demonstrated that the degree of implant failure is high in grafted bone and may even reach 25% in extensive defects.…”

Systematic review on diabetes mellitus and dental implants: an update

“…Five studies showed no negative influence [ 10 , 11 , 38 , 42 , 44 ], two showed a non-significant [ 29 , 36 ] and six a significantly negative influence of diabetes on implant survival [ 12 , 16 , 32 , 37 ]. For example, the study of Alberti et al [ 38 ] showed no significant difference of the implant survival after 10 years in patients with diabetes (survival rate of 96.5%) compared to patients without diabetes mellitus (survival rate of 94.8%), whereas the study of French et al [ 37 ] identified diabetes mellitus with a hazard ratio of 2.25 as a risk factor for implant failure in a multivariate analysis, implicating an over two times higher risk for failure of dental implants in patients with diabetes mellitus. In addition, eight aggregated literature references could be included on this question, whereby in seven publications, it was concluded that diabetes mellitus does not seem to have a significant influence on implant survival [ 8 , 51 , 52 , 55 – 58 , 63 ].…”

Peri-implant disease: early diagnosis and non-surgical treatment—a narrative literature review

“…Patients with uncontrolled diabetes mellitus were reported to be at a greater risk for developing peri-implant diseases (7,22,57,58). In a recent meta-analysis, diabetic patients were at 1.46 times greater risk for developing peri-implantitis than non-diabetic patients (57).…”