Long‐term clinical outcomes of external beam radiation therapy for oligometastatic prostate cancer: A combination of prostate‐targeted treatment and metastasis‐directed therapy

Abstract

Abbreviations & Acronyms 3D-CRT = three-dimensional conformal radiotherapy A-ADT = adjuvant androgen deprivation therapy ADT = androgen deprivation therapy ARAT = androgen receptor axistargeted BF = biochemical failure CAB = combined androgen blockade CF = clinical failure CI = confidence interval CRPC = castration-resistant prostate cancer CT = computed tomography EBRT = external beam radiation therapy IMRT = intensity-modulated radiation therapy iPSA = pretreatment prostatespecific antigen LH-RH = luteinizing hormonereleasing hormone analog MDT = metastasis-directed therapy MRI = magnetic resonance imaging NA-ADT = neoadjuvant androgen deprivation therapy OMPCa = oligometastatic prostate cancer OS = overall survival PCSS = prostate cancer-specific survival PSA = prostate-specific antigen PTT = prostate-targeted treatment WPRT = whole pelvic radiation therapy

Editorial Comment to Long‐term clinical outcomes of external beam radiation therapy for oligometastatic prostate cancer: A combination of prostate‐targeted treatment and metastasis‐directed therapy

“…3 For synchronous OMPCa, a large prospective trial (STAM-PEDE) showed improved survival with prostate-targeted treatment in patients with low metastatic burdens. 1 Aizawa et al 4 report that the addition of metastasis-targeted treatment to prostate-targeted treatment in patients with synchronous OMPCa resulted in good, long-term, disease-free survival with acceptable complications, a finding that has not been adequately investigated. It is hoped that the results of prospective studies will confirm the usefulness of this treatment.…”