Long-term Clinical Outcome After Lyme Neuroborreliosis in Childhood

Abstract

The long-term clinical recovery rate was 73% in children with confirmed LNB. Persistent facial nerve palsy occurred in 13%, whereas other motor or sensory deficits were found in another 14%. Neurologic deficits did not affect daily activities or school performance more often among patients than controls and should be considered as mild. Furthermore, nonspecific subjective symptoms such as headache, fatigue, or memory or concentration problems were reported as often among patients as controls and should not be considered as sequelae after LNB.

Serological, clinical and epidemiological aspects of Lyme borreliosis in Mures County, Romania

“…The facial nerve involvement in our study was seen in a child and a young adult and was not accompanied by CSF pleocytosis, a clinical aspect known as acute meningoradiculitis or Bannwarth syndrome, the most typical manifestation of early LB [20].…”

Diplégie faciale révélatrice d’une maladie de Lyme

“…Ainsi, notre patient a présenté une régression complète de la diplégie faciale durant les deux semaines suivant l'instauration du traitement par ceftriaxone. Cependant, dans une série récente, Skogman et al [25] ont constaté que 13 % des patients présentaient des séquelles de paralysie faciale. En 2013, dans une série regroupant 50 patients atteints de neurroborréliose, Eikeland et al [26] ont signalé que les facteurs suivants étaient prédictifs de la survenue de séquelles : un retard à l'institution de l'antibiothérapie, une atteinte multisystémique, une absence de régression complète des manifestations cliniques après 4 mois de traitement ; par contraste, les anomalies du liquide céphalo-rachidien ne constituaient pas un facteur pronostique chez ces patients.…”

Lyme borreliosis: reviewing potential vaccines, clinical aspects and health economics

“…Manifestations are slightly different in children than in adults with shorter duration of symptoms and better prognosis [72]. Clinical manifestations of LB can generally be divided into three stages, labeled early Lyme disease (stage 1), early disseminated Lyme disease (stage 2) and late disseminated Lyme disease (stage 3), associated with diverse disease symptoms and durations for developing symptoms after the infectious tick bite [73].…”