Long-term clinical and functional results of sleeve lobectomy for primary lung cancer

Deslauriers, Jean; Gaulin, Paul; Beaulieu, M; Piraux, Michel; Bernier, Raymond; Cormier, Yvon

doi:10.1016/s0022-5223(19)35847-7

Cited by 84 publications

(12 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Indeed, our findings and other studies have shown that SR is a safe procedure with good outcomes. 4 –6 In our series despite the fact that more that 25% of the cases were complex SR, the peri-operative mortality and 5-year survival were comparable to those of Lausberg and colleagues 7 who reported a mortality for complex sleeves of less than 2%, and 5-year survival of 43%. In agreement with other reports, we also found that patients who underwent pneumonectomy had significantly more advanced disease (25% more had stage III with N2 disease) and larger tumor sizes than those who received a sleeve resection.…”

Section: Discussionsupporting

confidence: 75%

Comparative Analysis and Outcomes of Sleeve Resection versus Pneumonectomy

Parissis

Leotsinidis

Hughes

et al. 2009

Asian Cardiovasc Thorac Ann

View full text Add to dashboard Cite

To compare the outcome of sleeve resection or complex sleeve resection versus (Vs) pneumonectomy for lung cancer in a single unit. Between 1998 and 2006, 664 lung resections were carried out. There were 129 (19.4%) pneumonectomies and 79 (11.9%) sleeve resections; Twenty one patients (26.5%) underwent a complex sleeve resection. Operative mortality for the sleeve resections (SR) was 2.5% and for the pneumonectomies 8.53%. Overall 5-year survival after SR was 46.8% and after pneumonectomy 37.1%. The survival curves for the 2 procedures after adjusting for risk factors are different. The area under the curve is higher for the SR (Hazard ratio 1.78 C.I.: 0.92-3.46). The 5-year survival for early stages favors SR. The survival for the complex SR was not influenced by the complexity of the procedure but from the TNM stage of each individual case. Multivariate analysis of risk factors affecting survival after surgery showed: male sex Hazard ratio (HR) 1.19, 0.63-2.27(95%CI), Age >63 1.38(HR), 0.78-2.48, Pneumonectomy 1.78(HR), 0.92-3.46 and stage III 4.44(HR), 1.94-10.16(95% CI). For comparative stages survival appears to be better after sleeves, moreover male sex, sleeve resection, age younger that 63 and early TNM stage are positive predictors for survival.

show abstract

Section: Discussionsupporting

confidence: 75%

Comparative Analysis and Outcomes of Sleeve Resection versus Pneumonectomy

Parissis

Leotsinidis

Hughes

et al. 2009

Asian Cardiovasc Thorac Ann

View full text Add to dashboard Cite

show abstract

“…Comparisons of sleeve lobectomy with pneumonectomy in terms of postoperative lung function and quality of life favor sleeve lobectomy. 2,12 Although we were not sure whether preservation of the middle lobe (2 segments) would have an influence on postoperative lung function, the lung volumes at 3 months postoperatively showed an overall increase of FEV 1 after sleeve lobectomy. This may be explained by a recovery of function of the preserved middle lobe after removal of the tumor in the lower lobe (better ventilation or perfusion on the right side).…”

Section: Discussionmentioning

confidence: 96%

“…5 Bronchoplastic procedures have been shown to offer better long-term survival and quality of life in terms of improved postoperative lung function. 2,7,12…”

Section: Discussionmentioning

confidence: 99%

Preserving Middle Lobe to Improve Lung Function in Non-Small-Cell Lung Cancer

Ludwig

Morand

Schnell

et al. 2009

Asian Cardiovasc Thorac Ann

View full text Add to dashboard Cite

When a lung tumor arises in segment 6, the close anatomical relationship to the middle lobe bronchus may make a lower bilobectomy necessary. Sleeve lobectomy may be an alternative. These procedures were compared retrospectively in 36 patients operated on between January 2005 and December 2006 with non-small-cell lung cancer (stage I-IIIB) of the right lower lobe. Sleeve lobectomy was performed in 21 patients and bilobectomy in 15 (41%). Preoperative lung function was comparable in both groups. Radical resection was achieved in 34/36 patients. Operation time was 121 min for sleeve lobectomy and 144 min for bilobectomy. Chest tubes were removed after 5 days in both groups. Postoperative lung function was better after sleeve lobectomy than bilobectomy (forced expiratory volume in 1st sec: 78% vs. 69%). Preservation of the middle lobe by sleeve lobectomy is feasible. There was no evidence that this resection was less radical, and complication rates were similar in both groups.

show abstract

“…Retention of secretions may be associated with bronchial denervation, which has been shown to decrease mucociliary clearance and viscoelasticity of bronchial secretions [ 17 ]. The reported incidence varies from 4 to 12% [ 18 ]. We did not perform repetitive bronchoscopy for bronchial clearing, and there were no postoperative complications.…”

Section: Discussionmentioning

confidence: 99%

Outcomes of Sleeve Lobectomy versus Pneumonectomy for Lung Cancer

Lee

Kim

et al. 2011

Korean J Thorac Cardiovasc Surg

View full text Add to dashboard Cite

BackgroundSleeve lobectomy for lung cancer in close proximity to or involving the carina is widely accepted. Operative morbidity and mortality rates, recurrence, and survival rates have varied considerably across studies.Materials and MethodsFrom March of 2005 to July of 2010, sleeve lobectomy was performed in 19 patients and pneumonectomy was performed in 20 patients. In this paper, the results of sleeve lobectomy and pneumonectomy for patients with lung cancer will be compared and evaluated.ResultsThere were no postoperative complications in either group, but there was one mortality in the pneumonectomy group. There was better preservation of pulmonary function in the sleeve lobectomy group than the pneumonectomy group (p=0.066 in FVC, p=0.019 in FEV1). The 3-year survival rates were 46.7% in the sleeve lobectomy group and 54.5% in the pneumonectomy group (p=0.505). The 3-year disease-free survival rates were 38% in the sleeve lobectomy group and 45.8% in the pneumonectomy group (p=0.200).ConclusionSleeve lobectomy for lung cancer showed low mortality, low bronchial anastomotic complication rates, and good preservation of pulmonary function.

show abstract

Long-term clinical and functional results of sleeve lobectomy for primary lung cancer

Cited by 84 publications

References 25 publications

Comparative Analysis and Outcomes of Sleeve Resection versus Pneumonectomy

Comparative Analysis and Outcomes of Sleeve Resection versus Pneumonectomy

Preserving Middle Lobe to Improve Lung Function in Non-Small-Cell Lung Cancer

Outcomes of Sleeve Lobectomy versus Pneumonectomy for Lung Cancer

Contact Info

Product

Resources

About