Long-term benzodiazepine users in family practice: differences from short-term users in mental health, coping behaviour and psychological characteristics

Zandstra, S.M.; Rijswijk, Eric van; Rijnders, C.A.Th.; Lisdonk, E.H. van de; Bor, Jacob; Weel, Chris van; Zitman, Frans G.

doi:10.1093/fampra/cmh309

Cited by 41 publications

(37 citation statements)

References 7 publications

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“…Benzodiazepines and antidepressants are often combined in the treatment of depression. This relationship between benzodiazepines and antidepressants was not seen in this study, but has been reported elsewhere [10,14,37,38]. As mentioned previously, a change in benzodiazepine prescribing was seen between baseline and the first postintervention period.…”

Section: Discussionsupporting

confidence: 71%

General Practitioners reduced benzodiazepine prescriptions in an intervention study: a multilevel application

Stewart

Niessen²,

Broer³

et al. 2007

Journal of Clinical Epidemiology

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Section: Discussionsupporting

confidence: 71%

General Practitioners reduced benzodiazepine prescriptions in an intervention study: a multilevel application

Stewart

Niessen²,

Broer³

et al. 2007

Journal of Clinical Epidemiology

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“…Based on previous studies, various potential determinants of BZD use and adequacy of BZD use were included and grouped into sociodemographic characteristics (age, gender, education, marital status and work status), psychological characteristics (current psychopathology, health care setting, severity of anxiety or depression symptoms; insomnia; antidepressant use, and personality traits) and physical characteristics (number of chronic diseases, medical consumption, pain complaints and smoking) [5, 12–15, 29, 32–34, 40].…”

Section: Methodsmentioning

confidence: 99%

“…dosage and number of BZD types used). In those studies, sex [29–31], age [28–33], education [32], psychopathology [32–34], physical health [30, 33, 34], pain complaints [34], daily BZD use [28], use of higher potency BZDs [31] and antidepressants [33] were identified as correlates of long‐term BZD use.…”

Section: Introductionmentioning

confidence: 99%

Correlates of (inappropriate) benzodiazepine use: the Netherlands Study of Depression and Anxiety (NESDA)

Manthey

Veen

Giltay

et al. 2011

Brit J Clinical Pharma

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WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• Benzodiazepines (BZDs) are not only used as a treatment for anxiety and depression (besides epilepsy), but also inappropriately for chronic insomnia, pain, somatic illnesses [1] and uncontrollable stress.• In spite of lack of effectiveness and adverse health consequences in chronic BZD use, over 50% are long-term users.• The relative importance of sociodemographic, psychological and physical determinants of BZD use in general and inappropriate use has never been investigated in a comprehensive, multivariable model. WHAT THIS STUDY ADDS• BZDs were used by a considerable proportion of the NESDA participants and BZD use was rarely in accordance with all guidelines, mainly because of an extended duration of use.• Mentally or physically vulnerable subjects were most likely to use BZDs as well as to use it inappropriately.• Clinicians should be vigilant when initiating BZD prescriptions for vulnerable subjects, particularly when patients are chronically ill and old, as those subjects are at high risk of inappropriate use. AIMResults on determinants of benzodiazepine (BZD) use in general and inappropriate use were inconsistent and mostly univariate. The relative importance of sociodemographic, psychological and physical determinants has never been investigated in a comprehensive, multivariate model. METHODSWe included 429 BZD users and 2423 non-users from the Netherlands Study of Depression and Anxiety (NESDA) in order to investigate sociodemographic, psychological and physical determinants of BZD use and inappropriate use by logistic and linear regression analyses. RESULTSBZDs were used by a considerable proportion of the 2852 NESDA participants (15.0%

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“…Former studies have also attempted to characterize individual socio-demographic factors associated with the occurrence of long-term use of benzodiazepines. Some of the most consistent predictors of long-term use of benzodiazepines are older age (Andersen and Frydenberg, 2011;Cunningham et al, 2010;Demyttenaere et al, 2008;Fang et al, 2009) and low socio-economic status (Andersen and Frydenberg, 2011;Demyttenaere et al, 2008;Sonnenberg et al, 2012;Zandstra et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Socio-demographic factors and long-term use of benzodiazepines in patients with depression, anxiety or insomnia

Sjöstedt

Sundquist

2017

Psychiatry Research

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Long-term benzodiazepine users in family practice: differences from short-term users in mental health, coping behaviour and psychological characteristics

Abstract: The associations found point to possibilities to reduce long-term benzodiazepine use, for example if patients with these characteristics are treated with the alternatives to benzodiazepines or are monitored closely for a short period after being prescribing benzodiazepines.

Cited by 41 publications

References 7 publications

General Practitioners reduced benzodiazepine prescriptions in an intervention study: a multilevel application

General Practitioners reduced benzodiazepine prescriptions in an intervention study: a multilevel application

Correlates of (inappropriate) benzodiazepine use: the Netherlands Study of Depression and Anxiety (NESDA)

Socio-demographic factors and long-term use of benzodiazepines in patients with depression, anxiety or insomnia

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