Long-Term Anticoagulant Therapy

Tulloch, J. A.; Wright, Irving S.

doi:10.1161/01.cir.9.6.823

Cited by 77 publications

(21 citation statements)

References 3 publications

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“…[25][26][27][28][29][30] In view of the high recurrence rate of acute peripheral arterial occlusions in our series as well as the high incidence of serious cardiovascular disease, the use of ambulatory anticoagulant therapy for the prevention of further clotting in the leg and elsewhere in the circulation would appear to be justified.…”

Section: -20mentioning

confidence: 99%

Studies in Peripheral Arterial Occlusive Disease

Wessler¹,

Sheps²,

Gilbert³

et al. 1958

Circulation

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Material for an analysis of the pathogenesis and course of acute peripheral arterial ocelusion was provided by patients with acute arterial occlusion in a lower extremity, special arterial injection studies of amputated limbs, arteriograms performed on cadavers, and data from nai experimental investigation of acute femoral artery embolism in dogs. This correlative study offers a basis for the evaluation of procedures recomaniended for the prophylaxis and treatment of acute isehemia.

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Section: -20mentioning

confidence: 99%

Studies in Peripheral Arterial Occlusive Disease

Wessler¹,

Sheps²,

Gilbert³

et al. 1958

Circulation

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“…The proportionate reduction in the risk of reinfaretion achieved by the high dose regimen is slightly greater among patients with a previous history of one or more infarets, but the difference is not statistically significaint. 5. The difference in the death rate is most evident in the first six months of the follow-up period, but the disparity and the reinfaretion rate is maintained for at least two years in the follow-up period.…”

Section: The Same Trends Appear Even More Clearlymentioning

confidence: 95%

Symposium on Coronary Heart Disease

Wright

1960

Circulation

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“…In addition even though several texts have recommended a decreasing dosage or cessation of the drug before treatment, the number of days suggested for the altered medication regimen before the initiation of treatment varies from two to six days. [66][67][68] This increases the risk of thromboembolism, 7,69,70 particularly in patients with artificial valves. 9,14 In addition, the theory of rebound hypercoagulability after withdrawal of warfarin has been supported by studies that show increased thrombin activity after warfarin withdrawal.…”

Section: ) Decreasing the Level Of Anticoagulation Or Temporarily DImentioning

confidence: 99%

Current concepts of the management of dental extractions for patients taking warfarin

Carter

Goss

Lloyd

et al. 2003

Australian Dental Journal

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Background: Controversy has surrounded the correct management of patients therapeutically anticoagulated with warfarin who require dental extractions. The risk of bleeding must be weighed up against the risk of thromboembolism when deciding whether to interfere with a patient's warfarin regimen. An improved understanding of the importance of fibrinolytic mechanisms in the oral cavity has resulted in the development of various local measures to enable these patients to be treated on an outpatient basis. Methods: A review of the literature was undertaken. This was supplemented by the authors' clinical trials and extensive clinical experience with anticoagulated patients. Results: Various protocols for treating patients taking warfarin have been reviewed and summarized and an overview of the haemostatic and fibrinolytic systems is presented. A protocol for management of warfarinized patients requiring dental extractions in the outpatient setting is proposed. Conclusions: Patients therapeutically anticoagulated with warfarin can be treated on an ambulatory basis, without interruption of their warfarin regimen provided appropriate local measures are used.

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Long-Term Anticoagulant Therapy

Cited by 77 publications

References 3 publications

Studies in Peripheral Arterial Occlusive Disease

Studies in Peripheral Arterial Occlusive Disease

Symposium on Coronary Heart Disease

Current concepts of the management of dental extractions for patients taking warfarin

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