Long-term angiographic follow up, cardiac events, and survival in patients undergoing percutaneous transluminal coronary angioplasty.

Ernst, Sjef M.P.G.; Feltz, Taco A. van der; Bal, Egbert T.; Bogerijen, Leo van; Berg, E. Van Den; Ascoop, C. A. P. L.; Plokker, H.W. Thijs

doi:10.1136/hrt.57.3.220

Cited by 61 publications

(6 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although these data are consistent with those from some previous studies [4,5,7,9,12,18,19], they are not in agreement with two other reports which have indicated an increased risk of restenosis in patients suffering from unstable angina prior to the time of coronary angioplasty [10,17]. However, comparison between the few published reports on angioplasty for stable and unstable angina must be done with caution for a number of reasons.…”

Section: Incidence Of Restenosiscontrasting

confidence: 46%

See 1 more Smart Citation

Angioplasty for stable versus unstable angina pectoris: Are unstable patients more likely to get restenosis?

Luijten¹,

Beatt²,

Feyter³

et al. 1988

Int J Cardiac Imag

View full text Add to dashboard Cite

Current evidence with regard to the possible association between clinical expression of coronary disease prior to the time of angioplasty, and the subsequent risk of restenosis following successful dilatation, remains inconclusive. To prospectively compare the incidence of restenosis in stable versus unstable angina pectoris patients, follow-up angiography was performed in 85 percent of patients from a consecutive series with a successful PTCA, irrespective of presence or absence of recurrent ischemic symptoms. Furthermore, changes in lesion severity were assessed quantitatively by an automated edge-detection technique rather than visual analysis. Employing such a study design and follow-up protocol, it was found that the incidence of restenosis in patients with stable coronary artery disease was similar to that of patients with unstable rest angina, irrespective of the type of angiographic definition used.

show abstract

Section: Incidence Of Restenosiscontrasting

confidence: 46%

“…Whereas some previous reports have indicated that angioplasty for unstable angina is associated with an increased risk of lesion recurrence as compared with stable angina [10,17], this has not been corroborated by others [4,5,7,9,12,18,19].…”

Section: Introductionmentioning

confidence: 66%

Angioplasty for stable versus unstable angina pectoris: Are unstable patients more likely to get restenosis?

Luijten¹,

Beatt²,

Feyter³

et al. 1988

Int J Cardiac Imag

View full text Add to dashboard Cite

show abstract

“…Magnesium concentration in various organs [77][78][79] does not correlate with serum magnesium level, and normal serum magnesium levels may exist in the presence of low tissue levels [38,80,8]].…”

Section: Ho!vieostasis Of Magnesiummentioning

confidence: 99%

Effect of magnesium on restenosis after percutaneous transluminal coronary angioplasty: a clinical and angiographic evaluation in a randomized patient population

Roth

Eshchar

Keren

et al. 1994

European Heart Journal

View full text Add to dashboard Cite

Restenosis is a major clinical problem following successful percutaneous transluminal coronary angioplasty. Since magnesium has vasodilator and antithrombotic effects, this study was designed to evaluate its potential to decrease the rate of restenosis. In an open-labelled, randomized controlled study, 148 patients underwent successful coronary angioplasty. Ninety-eight patients were treated with 46-52 mmol/18-20 h intravenous magnesium sulphate (groups M1 and M2), and 49 of them continued with oral supplements of magnesium hydroxide 600 mg.day-1 (group M2). The other 50 patients served as controls (group C). Coronary angiography was performed before, immediately after and at 6 months follow-up or earlier if clinically indicated. Clinical, laboratory, ergometric and radionuclide evaluations were also carried out. One hundred and thirty-nine patients (94%) with 163 dilated segments completed the study. Intravenous magnesium was well tolerated. The cross-sectional area at the site of angioplasty increased by 3.55 +/- 2.01 mm2 in groups M1 and M2 compared with an increase of 2.90 +/- 1.63 mm2 in the control group, (P = 0.03). A trend towards a lower rate of restenosis (> 50% reduction in luminal diameter) was noticed in the magnesium groups (28/110, 25%) compared with the control group (20/53, 38%) P = 0.10. Oral administration of magnesium was well tolerated, did not have an additive effect on restenosis, but an improved clinical course was noted. It is concluded that intravenous administration of magnesium in patients undergoing coronary angioplasty is feasible and safe and that the beneficial trend of magnesium to prevent acute recoil and late (within 6 months) restenosis is encouraging and should promote further investigation in a larger patient population.

show abstract

“…57 The importance of intimal hyperplasia in the process of restenosis is also shared by both humans and atherosclerotic rabbits. 4 " 8 An advantage of this model is the opportunity for the correlation of histology with angiographic features and the ability to measure serial pharmacological effects of a variety of agents.…”

Section: Limitations Of the Modelmentioning

confidence: 99%

Potentiation of the vasospastic response to angioplasty by pretreatment with fluoxetine. A study in the atherosclerotic rabbit.

Sigal

Gellman

Anderson

et al. 1993

Arterioscler Thromb

View full text Add to dashboard Cite

Long-term angiographic follow up, cardiac events, and survival in patients undergoing percutaneous transluminal coronary angioplasty.

Cited by 61 publications

References 6 publications

Angioplasty for stable versus unstable angina pectoris: Are unstable patients more likely to get restenosis?

Angioplasty for stable versus unstable angina pectoris: Are unstable patients more likely to get restenosis?

Effect of magnesium on restenosis after percutaneous transluminal coronary angioplasty: a clinical and angiographic evaluation in a randomized patient population

Potentiation of the vasospastic response to angioplasty by pretreatment with fluoxetine. A study in the atherosclerotic rabbit.

Contact Info

Product

Resources

About