Long-term administration of prostaglandin E1 Report of two cases with tetralogy of Fallot and esophageal atresia

Abe, Kazuo; Shimada, Yasuhiro; Takezawa, Jun; Oka, Norifumi; Yoshiya, Ikuto

doi:10.1097/00003246-198203000-00003

Cited by 10 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The metabolism is decreased in cyanotic heart disease because of decreased pulmonary blood flow lead-J. We made a similar observation that ALP activity can be used as a marker for PGE 1 Med.…”

Section: Discussionmentioning

confidence: 74%

Prostaglandin induced cortical hyperostosis in neonates with cyanotic heart disease

Nadroo¹,

Shringari²,

Garg³

et al. 2000

Journal of Perinatal Medicine

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 74%

Prostaglandin induced cortical hyperostosis in neonates with cyanotic heart disease

Nadroo¹,

Shringari²,

Garg³

et al. 2000

Journal of Perinatal Medicine

View full text Add to dashboard Cite

show abstract

“…У детей со средней или легкой степенью гипертрофии выводного отдела правого желудочка в первые недели жизни эпизоды цианоза могут не наблюдаться. Однако с течением времени нарастание гипертрофии выводного отдела правого желудочка приводит к увеличению объема обедненной кислородом крови в системном кровотоке и к выраженной гипоксемии, клинически проявляющейся приступами центрального цианоза [9]. Таким образом, новорожденным со значительным сужением выводного отдела, неадекватным легочным кровотоком, выраженными гипоксемией и цианозом может потребоваться проведение первого этапа оперативной коррекции порока в кратчайшие сроки.…”

Section: ключевые словаunclassified

The experience of using the atenolol at newborns with tetralogy of Fallot

Maslennikova¹,

Bokeriya²,

Degtyarev³

2020

Neonatology: News, Opinions, Training

View full text Add to dashboard Cite

show abstract

Indomethacin does not inhibit the anabolic effect of parathyroid hormone on the long bones of rats

Gera

Hock²,

Gunness-Hey

et al. 1987

Calcif Tissue Int

View full text Add to dashboard Cite

Chronic administration of parathyroid hormone, hPTH 1-34, increased bone mass in normocalcemic, young rats. Since PTH can stimulate prostaglandin E2 (PGE2) production in bone in vitro, and since PGE2 can stimulate bone formation, the anabolic effect of PTH could be mediated by PGE2. To test this hypothesis, experiments were done to determine if indomethacin, which blocks endogenous PG production, would inhibit the anabolic response of bone to PTH. In the first experiment, male Sprague-Dawley rats, 70-100 g, in groups of five, were treated for 12 days with either hPTH 1-34, 8 micrograms/100g/day; PTH vehicle; indomethacin, 2 mg/kg/day; or a combination of PTH and indomethacin. In the second experiment, groups of 6 rats each were given vehicle or hPTH 1-34, 8 micrograms/100g/day, in combination with indomethacin, 0, 1, 2, or 4 mg/kg/day. Subcutaneous injections of PTH wee given once daily and indomethacin was given orally in divided doses, twice a day. Rats were killed on day 12 in both experiments; their sera were analyzed and the trabecular and cortical bone of distal femurs processed to determine calcium (Ca) and hydroxyproline content and dry weight. PTH and indomethacin had no significant effect on serum Ca, phosphate, alkaline phosphatase, urea nitrogen and creatinine, or systemic and long-bone linear growth. In rats treated with PTH alone or in combination with indomethacin, bone Ca of distal femurs increased by 28-44%; dry weight by 29-41%, and hydroxyproline by 17-45%. Indomethacin alone had no effect on bone growth.(ABSTRACT TRUNCATED AT 250 WORDS)

show abstract

Long-term administration of prostaglandin E1 Report of two cases with tetralogy of Fallot and esophageal atresia

Cited by 10 publications

References 0 publications

Prostaglandin induced cortical hyperostosis in neonates with cyanotic heart disease

Prostaglandin induced cortical hyperostosis in neonates with cyanotic heart disease

The experience of using the atenolol at newborns with tetralogy of Fallot

Indomethacin does not inhibit the anabolic effect of parathyroid hormone on the long bones of rats

Contact Info

Product

Resources

About