Long-term (≥15 years) Follow-up of Percutaneous Coronary Intervention of Unprotected Left Main (From the GRAVITY Registry)

D’Ascenzo, Fabrizio; Elia, Edoardo; Marengo, Giorgio; Wańha, Wojciech; González‐Ferreiro, Rocío; Truffa, Alessandra; Trabattoni, Daniela; Figini, Filippo; Verardi, Roberto; Palma, Gaetano Di; Infusino, Fabio; Pivato, Carlo Andrea; Ochała, Andrzej; Omedè, Pierluigi; Milewski, Marek; Estevez, R; Roubin, S. Raporeiras; Filippo, Ovidio De; Conrotto, Federico; Montefusco, Antonio; Gili, Sebastiano; Cortese, Bernardo; Dusi, Veronica; Gallone, Guglielmo; Manfredi, Roberto; Mancone, Massimo; Zoccai, Giuseppe Biondi; Casella, Gianni; Templin, Christian; Wojakowski, Wojciech; Sheiban, Imad; Ferrari, Gaetano Maria De

doi:10.1016/j.amjcard.2021.06.008

Cited by 3 publications

(1 citation statement)

References 17 publications

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“…Calcified Left Main (LM) stenosis represents a high-risk subset for percutaneous coronary intervention (PCI), and it has been recognized as a marker for increased rates of periprocedural complications and worse long-term outcomes [ 1 , 2 ]; therefore, according to the current revascularization guidelines [ 3 ], the coronary artery bypass grafting (CABG) remains as the preferred revascularization strategy. However, in clinical practice, the high surgical risk and coexisting comorbidities require the PCI to function as a reasonable alternative for selected patients.…”

Section: Introductionmentioning

confidence: 99%

Intravascular Lithotripsy as a Novel Treatment Method for Calcified Unprotected Left Main Diseases—Comparison to Rotational Atherectomy—Short-Term Outcomes

Rola

Kulczycki²,

Włodarczak

et al. 2022

IJERPH

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Background: The unprotected calcified Left Main disease represents a high-risk subset for percutaneous coronary intervention (PCI), and it is associated with a higher number of periprocedural complications and an increased rate of in-stent thrombosis and restenosis. Adequate lesion preparation plays a crucial role in achieving a favorable PCI outcome. Rotational Atherectomy (RA) is a well-established plaque-modifying method; nevertheless, the data regarding the effectiveness of RA in LM diseases is scarce. Recently, the novel ShockWave-Intravascular-Lithotripsy(S-IVL) device has been introduced to the PCI armamentarium in order to modify the calcified plaque. Methods: We performed a retrospective evaluation of 44 consecutive subjects who underwent the LM-PCI, and who were supported by either the RA or S-IVL. Results: The Rota group consisted of 29 patients with a mean syntax score of 28.0 ± 7.5. The S-IVL group was composed of 15 subjects with a syntax score of 23.3 ± 13.0 There were no statistical differences regarding MACE between the RA and Shockwave arms of the in-hospital group (10.3% vs. 6.7%), or in the six month (17.2% vs. 13.3%) follow-up group. Conclusions: RA and S-IVL could be safe and effective therapeutic strategies for calcified LM disease. Further studies with a higher number of participants and longer follow-up times are warranted to establish the potential benefits of RA and S-IVL for the management of LM stenosis.

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Section: Introductionmentioning

confidence: 99%