Long-term (10-year) monitoring of transposon-mediated transgenic cattle
Soo-Young Yum,
Bae Young Choi,
Gyeong-Min Gim
et al.
Abstract:The production of transgenic animals using non-viral methods has raised questions regarding their long-term health and genomic stability. In this study, we evaluated these aspects in transgenic cattle over ten years, using transposon-mediated gene transfer. Our longitudinal analysis included a comprehensive health assessment and whole-genome DNA resequencing. We found no significant alterations in physiological parameters or health complications in transposon-mediated transgenic cattle that exceeded 10 years o… Show more
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