Long‐<scp>T</scp>erm Results after Carotid Stent Implantation

Radu, Heike; Bertog, Stefan; Robertson, Greg; Franke, Jennifer; Rabe, Kasja; Hornung, Marius; Vaškelytė, Laura; Hofmann, Ilona; Sievert, Horst

doi:10.1111/joic.12077

Cited by 4 publications

(7 citation statements)

References 15 publications

(19 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Currently, carotid artery stenosis due to carotid atherosclerosis is treated with drugs, carotid endarterectomy (CEA), and carotid artery stenting (CAS). Although CEA has been regarded a the criterion standard in the treatment of carotid artery stenosis [4], CAS has been widely applied in the treatment of carotid artery stenosis because it does not need general anesthesia, is minimally invasive, and has definite effectiveness during the progression of techniques and materials used for neurological interventions [5,6]. …”

Section: Introductionmentioning

confidence: 99%

Influence of Carotid Artery Stenting on Cognition of Elderly Patients with Severe Stenosis of the Internal Carotid Artery

et al. 2014

View full text Add to dashboard Cite

BackgroundThe aim of this study was to investigate the influence of carotid artery stenting (CAS) on the cognition and quality of life of elderly patients with severe stenosis of the internal carotid artery.Material/Methods65 elderly patients with symptomatic severe stenosis of internal carotid artery were recruited into 2 groups: the pharmacotherapy group (n=29) and the CAS group (n=36). Before surgery and 1, 3, 6, and 12 months after surgery, Montreal cognitive assessment (MoCA) was used for the evaluation of cognition and WHOQOL-BREF was used for the assessment of quality of life.ResultsAt 12 months after surgery, total MoCA score and WHOQOL-BREF score in the pharmacotherapy group was significantly reduced when compared with those before surgery (P<0.05). In the CAS group, the total MoCA score, scores of attention and delayed recall, and WHOQOL-BREF score increased significantly at different time points after surgery when compared with those before surgery (P<0.05). Moreover, in CAS group, the MoCA score and WHOQOL-BREF markedly increased gradually over time (P<0.05). Compared with the pharmacotherapy group, cognition and quality of life in the CAS group were improved dramatically during the follow-up period (P<0.05).ConclusionsSevere stenosis of the internal carotid artery is a cause of cognition impairment, and CAS may improve cognition and quality of life.

show abstract

Section: Introductionmentioning

confidence: 99%

Influence of Carotid Artery Stenting on Cognition of Elderly Patients with Severe Stenosis of the Internal Carotid Artery

et al. 2014

View full text Add to dashboard Cite

show abstract

“…The overall risk for the primary end point is also comparable with results from other high-volume centers, despite their generally shorter long-term follow-up. 8,[18][19][20] Furthermore, we were able to prevent neurological complications effectively: the observed annual risk for ipsilateral stroke (including the periprocedural period) of 0.6% in the overall cohort compares favorably with the 1.1% of the 10-year CREST data. 5 Our data also support the growing body of evidence that CAS results after the 30-day interval are durable; the flat course of the Kaplan-Meier curves signifying freedom from ipsilateral stroke.…”

Section: Long-term Outcomementioning

confidence: 70%

“…16 Some high-volume centers report lower event rates in their real-world populations of symptomatic and asymptomatic patients (range from 1.7% to 4.7%). 7,8,[17][18][19][20] However, 3 major issues need to be considered when comparing the current results with older reports. First, a strict, independent neurological assessment before and after the procedure was not mandatory in previous trials and even less so in registries.…”

Section: Procedural Outcomementioning

confidence: 81%

Long-Term Outcomes of Carotid Artery Stenting in Clinical Practice

Mudra

Staubach

Hein-Rothweiler

et al. 2016

Circ: Cardiovascular Interventions

View full text Add to dashboard Cite

Background-There is a lack of long-term data and data outside of controlled clinical trials in carotid artery stenting. Thus, we sought to evaluate the long-term effectiveness in stroke prevention by carotid artery stenting in a large number of patients in a real-world setting. Methods and Results-The present work represents an all-comer registry with a strict, prospectively designed, followup protocol, including an independent pre-and postprocedural neurological assessment. Between November 1999 and March 2015, 1000 procedures in 901 patients were consecutively performed in a single center. Mean age was 71±9 years, and symptomatic stenosis was present in 262 patients (29.1%). The population was also characterized by a high comorbidity: 289 patients (32.1%) would have been excluded according to the CREST protocol (Carotid Revascularization Endarterectomy Versus Stent Trial). The median length of follow-up was 5.5 (interquartile range, 2.6-7.9) years and complete in 93% of the patients.

show abstract

“…In our study, the patients with symptomatic severe carotid artery stenosis were treated with either carotid artery stenting or medication alone. Although carotid artery stenting and carotid endarterectomy have been recommended in symptomatic patients with moderate-severe (50-99%) stenosis and selected asymptomatic patients with severe (70-99%) stenosis, [5][6][7] there are still debates on the optimal medical and/or revascularization therapy for stroke prevention in symptomatic and asymptomatic patients in our country, especially in some local hospitals where patients with severe carotid artery stenosis (>70%) may be treated with medications alone in the initial stage of disease onset. If medications alone did not show any effect in a certain period of time, further treatment with carotid artery stenting or carotid endarterectomy may be performed.…”

Section: Discussionmentioning

confidence: 99%

“…[3,4] Prevention of mild cognitive impairment in carotid stenosis can control the development to dementia, and carotid endarterectomy and stenting are 2 established approaches for carotid artery atherosclerotic stenosis. [5][6][7] Since carotid artery stenting needs only local anesthesia, is minimally invasive and has definite effectiveness compared with carotid endarterectomy, it has been widely used for the treatment of carotid stenosis. Elimination of carotid artery stenosis will enable sufficient cerebral blood perfusion to the cerebral nerve cells and may consequently improve the cognitive impairment and function.…”

Section: Introductionmentioning

confidence: 99%

Effects of carotid artery stenting on cognitive impairment in patients with severe symptomatic carotid artery stenosis

et al. 2022

View full text Add to dashboard Cite

The effect of carotid artery stenting and medication on improvement of cognitive function in patients with severe symptomatic carotid artery stenosis is unknown. To investigate the effect of stenting compared with medication alone for severe carotid atherosclerotic stenosis on cognitive impairment. Patients with carotid stenosis and cognitive impairment were prospectively randomly divided into 2 groups of stenting or medication alone. Cognitive function was evaluated with the Montreal cognitive assessment (MoCA), Mini-Mental State Examination, and Barthel Index of Activities of Daily Living (BI). Continuous data in normal distribution were tested with the t-test but with the Mann-Whitney U test if not in normal distribution. Categorical data were presented as frequency and percentages and tested with the Fisher exact test. A P value < .05 was regarded as statistical significant. Carotid artery stenting was successfully performed in all patients (100%) in the stenting group. Compared with before treatment, the Mini-Mental State Examination, MoCA and BI scores at 6 months in the medication alone group and at 1, 3, and 6 months in the stenting group were significantly ( P < .005) improved. The stenting group had significantly ( P < .05) better scores than the medication alone group at the same time. At 6-month follow-up, the visuospatial/executive functions (3.69 ± 1.42 vs 2.42 ± 1.23), attention (5.24 ± 1.52 vs 3.63 ± 1.47), and language (2.64 ± 0.71 vs 1.96 ± 0.69) were significantly ( P < .05) improved in the stenting group compared with the medication alone group. Carotid artery stenting may significantly improve cognitive impairment and neurological function compared with medication alone in patients with severe carotid atherosclerotic stenosis concurrent with cognitive impairment.

show abstract

Long‐Term Results after Carotid Stent Implantation

Cited by 4 publications

References 15 publications

Influence of Carotid Artery Stenting on Cognition of Elderly Patients with Severe Stenosis of the Internal Carotid Artery

Influence of Carotid Artery Stenting on Cognition of Elderly Patients with Severe Stenosis of the Internal Carotid Artery

Long-Term Outcomes of Carotid Artery Stenting in Clinical Practice

Effects of carotid artery stenting on cognitive impairment in patients with severe symptomatic carotid artery stenosis

Contact Info

Product

Resources

About