Long Period Fiber Grating for Biosensing: An Improved Design Methodology to Enhance Add-Layer Sensitivity

Bandyopadhyay, Sankhyabrata; Villar, Ignacio Del; Basumallick, Nandini; Biswas, Palas; Dey, Tanoy Kumar; Bandyopadhyay, Somnath

doi:10.1109/jlt.2017.2754549

Cited by 22 publications

(8 citation statements)

References 19 publications

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“…From this data, the estimated sensitivity would be (28.6±0.4) pm/(g•mL -1 ). It is worth noting that some techniques have been proposed to improve this parameter by including additional layers of high refractive index as in [29]. Since we determined previously that the resolution of our system is 11 pm, we estimate the detection limit to be (385±5) ng•mL -1 .…”

Section: Proof Of Concept For Biosensingmentioning

confidence: 91%

Resonant Couplings in U-Shaped Fibers for Biosensing

Londero¹,

Delgado-Pinar²,

Cuadrado-Laborde

et al. 2023

J. Lightwave Technol.

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U-shaped tight curvatures in optical fibers lead to resonant couplings between the fundamental and higher order modes that are sensible to different parameters, such as strain or temperature, for example. The optical response of the sensor consists on the shift of the resonant wavelength of the coupling. In the case of singlemode fibers, the coupling involves a so-called "cladding mode" and, due to its evanescent field, the curved region will be sensible to changes in the external medium, as well. In this paper, we present the fabrication and characterization of a robust, easy-to-make, U-shaped fiber sensor based on singlemode telecom fiber and its application for biosensing. The resonant nature of the sensing mechanism presents the advantage of large dynamic ranges for RI variations without the ambiguity of other techniques such as interferometry. We studied the performance of the U-shaped fiber sensor for different bending radii, to optimize its sensitivity and detection limit at 1550 nm operation wavelength, as well as the effect of temperature on its response. The shift of the resonant wavelength was measured in detail as a function of the external RI within the range [1.33-1,37]; the detection limit was established in (3.71±0.03)×10 -5 RIU. Furthermore, the device was successfully tested as a proof of concept biosensor, using a system model antigen-antibody (BSA-aBSA.)

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Section: Proof Of Concept For Biosensingmentioning

confidence: 91%

Resonant Couplings in U-Shaped Fibers for Biosensing

Londero¹,

Delgado-Pinar²,

Cuadrado-Laborde

et al. 2023

J. Lightwave Technol.

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show abstract

“…The complete water sensing probe was then evaluated in the detection of Pb 2+ ions in water. To do so, a set of Pb 2+ solutions, of eleven different concentrations (0.5 nM, 1 nM, 2 nM, 3 nM, 4 nM, 5 nM, 10 nM, 50 nM, 100 nM, 500 nM, and 1000 nM), was prepared by optical properties of the externally deposited sensing layer (see recent work in the literature [27,29,44,49]).…”

Section: Evaluation Of Sensor Performance -Pb 2+ Ions In Watermentioning

confidence: 99%

Lead (Pb2+) ion sensor development using optical fiber gratings and nanocomposite materials

Ghosh

Dissanayake

Asokan

et al. 2022

Sensors and Actuators B: Chemical

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“…Surface-based changes can be occurred by two ways: 1) adsorption of mass of the biochemical analyte over the specific receptor layer which can be quantified by change in resonance wavelength λ resonance of a particular cladding mode with respect to thickness of a bio-analyte layer (depends on the deposited mass over the surface of the sensors) while the RI property of surrounding medium is remaining same and 2) A change in RI of the receptor layer after interaction with specific target analytes without altering the RI of the surrounding medium. The detailed quantification of these surface-based changes with "add-layer sensitivity" was described elsewhere [21], [22].…”

Section: Volume and Surface Changementioning

confidence: 99%

“…Surface plasmon resonance (SPR) based sensors, Quartz crystal microbalance (QCM), surface acoustic wave (SAW)-based sensors were used successfully for the quantification of localized surface change as a result of target analyte and receptor attachment during specific biochemical sensors [18]- [20]. Recently, the add-layer sensitivity of LPFG was illustrated elsewhere to quantify the surface-based changes during specific applications [21], [22]. In the case of FBG based sensors till now there are not enough studies are being accomplished for characterization of add-layer sensitivity for surface-based measurement purpose according to our knowledge.…”

Section: Introductionmentioning

confidence: 99%

Employing Higher Order Cladding Modes of Fiber Bragg Grating for Analysis of Refractive Index Change in Volume and at the Surface

et al. 2020

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In this work, a detailed study on volume and surface refractive index (RI) sensitivity of cladding modes for a fiber Bragg grating (FBG) based sensor is presented. Surface RI sensitivity of the cladding mode of FBGs has been illustrated and quantified with the concept of add-layer sensitivity for the first time to the best of our knowledge. A detailed investigation of mode transition of higher-order cladding modes has been revisited and important characteristics of the cladding modes are observed which could open a new designing path of fabrication and innovative way of the use of this family of optical fiber grating-based sensors. The effect of "mode transition" of higher-order cladding modes, higher operating wavelength for respective cladding mode and "mode stretching" effects are combined together to achieve higher volume and surface RI sensitivity of cladding mode of FBG. It has been shown numerically that with proper designing, sub-nanometer (∼0.04 nm) attachment of target analyte could be recognized by cladding mode of FBG which is quite promising for application in optical fiber grating bio-sensors. This critical designing method of FBG based surface refractometer would be very helpful in case of the fabrication of highly sensitive sensors for distinct biochemical applications.

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Long Period Fiber Grating for Biosensing: An Improved Design Methodology to Enhance Add-Layer Sensitivity

Cited by 22 publications

References 19 publications

Resonant Couplings in U-Shaped Fibers for Biosensing

Resonant Couplings in U-Shaped Fibers for Biosensing

Lead (Pb2+) ion sensor development using optical fiber gratings and nanocomposite materials

Employing Higher Order Cladding Modes of Fiber Bragg Grating for Analysis of Refractive Index Change in Volume and at the Surface

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