Long non-coding RNAs: emerging functional players in the pathobiology and progression of myeloid leukemia
Sangeeta Dutta,
Vijay Suresh Akhade,
Subhendu Roy Choudhury
et al.
Abstract:Advancements and innovations in transcriptomics and computational biology have revealed long non-coding RNAs (lncRNAs) as some of the major regulators of essential biological processes. Their restricted spatial and temporal expressions as well as ability to interact with nucleic acids (DNA and RNA) and proteins make them key players in chromosome integrity, genomic architecture, and transcriptional and post-transcriptional regulation. Their dysregulation has been associated with numerous diseases and pathologi… Show more
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