“…LncRNAs have been demonstrated to serve as regulators of immune response and inflammation in CD. They possess the capability to modulate the expression of pro-inflammatory cytokines, including TNF-α [ 52 ] and IL-6, IL-1β, and IL-12 [ 47 ]. LncRNAs such as LUCAT1 have been shown to regulate the activation and polarization of macrophages, which play a crucial role in the inflammatory process [ 24 ].…”