Long-lasting cerebral functional changes following moderate dose x-radiation treatment to the scalp in childhood: an electroencephalographic power spectral study.

Do Low Doses of Ionizing Radiation Affect the Human Brain?

“…Epidemiological data on radiation risks for cerebrovascular pathology (Ivanov et al, 2006;RCRM data;Shimizu et al, 1999;Preston et al, 2003) CHILDHOOD >1.3−1.5 Gy Delayed cerebral effects Yaar et al, 1982 …”

“…At the same time, evidence of delayed radiation brain damage (lower examination scores on scholastic aptitude, IQ, and psychological tests, completed fewer school grades, increased risk for mental hospital admissions, slightly higher frequency of mental retardation, and EEG abnormalities) was revealed 20 years after childhood scalp irradiation in average doses to the brain of only 1.3 Gy in a cohort of nearly 20,000 Israel children exposed to X-ray irradiation of the head for ringworm (tinea capitis) management (Yaar, Ron, Modan, Perets, & Modan, Data Science Journal, Volume 8, 24 September 20091980Yaar, Ron, Modan, Rinott, Yaar, & Modan, 1982;Ron, Modan, Flora, Harkedar, & Gurewitz, 1982). Among these persons 40 years after radiotherapy (the mean estimated radiation dose to the brain was 1.5 Gy), excessive relative risks per 1 Gy were observed for benign meningiomas and malignant brain tumors (Sadetzki, Chetrit, Freedman, Stovall, Modan, & Novikov, 2005).…”

EEG Patterns in Persons Exposed to Ionizing Radiation as a Result of the Chernobyl Accident

“…39,40,55 Predominant involvement of the left hemisphere, particularly the left frontotemporal region, in persons exposed to ionizing radiation was reported in our previous works 23,[29][30][31][32][33][34][35][36] and in studies of other authors. 60 Increased beta activity has been described as a "radiation trace" in the period remote from irradiation, 22 and an increase of delta activity has been described as a possible marker for assessing absorbed dose of ionizing radiation. 23,[28][29][30][31][32][33]35,36,58,59 We propose that the left (dominant) hemisphere is more vulnerable in right-handed men to whole-body irradiation than the right.…”

“…16 Changes of brain biopotentials were found directly at the time of irradiation with a dose rate of 0.13 mGy•s -1 that formed the total absorbed dose of 0.5 mGy only. 22 Even though the mature CNS is commonly considered to be extremely radioresistant, evidence is dramatically increasing in support of the exceptional radiosensitivity of the brain. Doses of ionizing radiation-induced EEG abnormalities were 20-50 times lower than those caused by histologically assessed brain pathology.…”

Whether ionizing radiation is a risk factor for schizophrenia spectrum disorders?

“…It was concluded that the impact of ionizing radiation on the developing brain produced CNS injury. Yaar et al (1979Yaar et al ( , 1980Yaar et al ( , 1982 studied spontaneous and evoked electric activity in the brain in those patients. EEG visual analysis revealed only slight deviations in electrical cerebral activity, but substantial b-power increase likely due to radiation.…”