Long Intergenic Non-Coding RNAs of Human Chromosome 18: Focus on Cancers
Pavel V. Ershov,
Evgeniy O. Yablokov,
Yuri V. Mezentsev
et al.
Abstract:Malignant neoplasms are characterized by high molecular heterogeneity due to multilevel deregulation of gene expression and cellular functions. It is known that non-coding RNAs, including long intergenic non-coding RNAs (lincRNAs), can play significant roles in cancer biology. The current review focuses on a systematical analysis of genomic, transcriptomic, epigenomic, interactomic, and literature data on 65 lincRNAs of human chromosome 18 in the context of pan-cancer studies. The entire group of lincRNAs can … Show more
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