“…On the other hand, psychological frailty explained the difficulty in taking medications both at baseline and follow-up, as well as loneliness (cross-sectional) and falls (longitudinal). These results can be supported by the evidence from other authors stating that poorer self-reported mental health can be associated with lower levels of medication adherence because of the decline at the cognitive level [51], more feelings of loneliness as a consequence of symptoms of depression, such as anhedonia, decreased vitality or low self-esteem [52] or a higher risk of falls that can be related to recurrent changes in cognition, behavior and mental state [53]. Moreover, our results showed that social frailty was associated with loneliness, falls, fear of falling and difficulty in taking medications in cross-sectional analyses, but for none of the adverse outcomes longitudinally.…”