Lokalisierter Morbus Darier

Wagner, G.; Díaz, Carolina; Weyers, Wolfgang

doi:10.1055/s-2004-826054

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2011

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“…Die therapeutischen Maß-nahmen zur Behandlung des M. Darier sollten daher auch zu einer raschen Abheilung der Effloreszenzen, Linderung der belastenden Begleiterscheinungen wie Schmerzen und Pruritus und einem möglichst langen rezidivfreien Intervall führen. Neben der symptomatischen Therapie mit topischen Retinoiden, Glukokortikosteroiden, antiseptischen, antibiotischen und keratolytischen Externa, kommen bei schweren Formen systemische Retinoide (Acitretin; seltener Isotretinoin) zur Anwendung [3,4,6,8].…”

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Successful treatment of Darier disease with oral alitretinoin

Barnstedt¹

2011

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A 18-year-old man with severe Darier disease was treated with alitretinoin 30 mg daily. In addition he used topical keratolytic agents. The duration of treatment was 52 weeks. First significant improvement was noted within one week after starting treatment. Itchiness and erythema, particularly on the head and in the chest area, decreased spontaneously after starting the treatment. From week 4 on a remarkable reduction in scaling, fissures and hyperkeratosis was observed. After 52 weeks the patient was clear of disease, except for residual symptoms on his chest. Treatment was well tolerated without any side effects.

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Section: Diskussionunclassified

Successful treatment of Darier disease with oral alitretinoin

Barnstedt¹

2011

Hautarzt

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Lokalisierter Morbus Darier

Cited by 1 publication

References 8 publications

Successful treatment of Darier disease with oral alitretinoin

Successful treatment of Darier disease with oral alitretinoin

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