“…The seminal work of Kreimer and Connes showed that there is an underlying Hopf-algebraic structure to the renormalization of quantum field theory (QFT) [28,29,61]. This new perspective has led to deep insights into QFT, and also to novel computational methods that have enabled significant progress in higher order perturbative computations [14,16,17,20,22,23,27,60,62,63,64,81,83,84,85,88,89,90,91]. The Hopf-algebraic formulation of QFT is inherently perturbative in nature, so an important open question is to understand how the non-perturbative features of QFT arise naturally within the perturbative Hopf algebra structure.…”