Lofgren's Syndrome-Acute Onset Sarcoidosis and Polyarthralgia: A Case Report

Byun, Chan Woo; Yang, Seung Nam; Yoon, Joon Shik; Kim, Se Hwa

doi:10.5535/arm.2013.37.2.295

Cited by 14 publications

(23 citation statements)

References 9 publications

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“…A more recent report of the National Health and Nutrition Examination Survey (NHANES) 1999–2002, indicated that only 4% of individuals aged 12 years and older met the whole grain recommendation [23]. In addition, most grain products consumed in the U.S. are highly refined and contain more starch but less fiber, vitamins, and minerals [24]. …”

Section: Introductionmentioning

confidence: 99%

“…With the aging population in countries such as the US [31], the implementation of cost-effective preventive measures such as diet is becoming increasingly important. In addition, grain consumption varies by race and ethnicity [24]. Information regarding ethnic differences in dietary sources of grain and their contribution to B vitamins can potentially be used to tailor nutrition education and intervention programs for specific ethnic groups.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Ethnic differences in grains consumption and their contribution to intake of B-vitamins: results of the Multiethnic Cohort Study

Sharma

Sheehy

Kolonel

2013

Nutr J

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BackgroundResearch indicates that a diet rich in whole grains may reduce the risk of prevalent chronic diseases, including cardiovascular disease, diabetes, and some cancers, and that risk for these diseases varies by ethnicity. The objective of the current study was to identify major dietary sources of grains and describe their contribution to B vitamins in five ethnic groups.MethodsA cross-sectional mail survey was used to collect data from participants in the Multiethnic Cohort Study in Hawaii and Los Angeles County, United States, from 1993 to 1996. Dietary intake data collected using a quantitative food frequency questionnaire was available for 186,916 participants representing five ethnic groups (African American, Latino, Japanese American, Native Hawaiian and Caucasian) aged 45–75 years. The top sources of grain foods were determined, and their contribution to thiamin, riboflavin, niacin, vitamin B6, and folic acid intakes were analyzed.ResultsThe top source of whole grains was whole wheat/rye bread for all ethnic-sex groups, followed by popcorn and cooked cereals, except for Native Hawaiian men and Japanese Americans, for whom brown/wild rice was the second top source; major contributors of refined grains were white rice and white bread, except for Latinos. Refined grain foods contributed more to grain consumption (27.1-55.6%) than whole grain foods (7.4-30.8%) among all ethnic-sex groups, except African American women. Grain foods made an important contribution to the intakes of thiamin (30.2-45.9%), riboflavin (23.1-29.2%), niacin (27.1-35.8%), vitamin B6 (22.9-27.5%), and folic acid (23.3-27.7%).ConclusionsThis is the first study to document consumption of different grain sources and their contribution to B vitamins in five ethnic groups in the U.S. Findings can be used to assess unhealthful food choices, to guide dietary recommendations, and to help reduce risk of chronic diseases in these populations.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Ethnic differences in grains consumption and their contribution to intake of B-vitamins: results of the Multiethnic Cohort Study

Sharma

Sheehy

Kolonel

2013

Nutr J

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“…Cutaneous involvement occurs in about 25 % of patients and usually manifests as erythema nodosum and lupus pernio [6]. An acute form of sarcoidosis characterized by erythema nodosum, bilateral hilar lymphadenopathy, and polyarthralgia or polyarthritis is called Löfgren's syndrome [16]. The liver is the third most commonly involved organ after the lymph nodes and the lungs.…”

Section: Discussionmentioning

confidence: 99%

Sudden unexpected death due to severe pulmonary and cardiac sarcoidosis

Ginelliová

Farkas

Iannaccone

et al. 2016

Forensic Sci Med Pathol

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In this paper we report the autopsy findings of a 57 year old woman who died unexpectedly at home. She had been complaining of shortness of breath, episodes of dry coughing, and nausea. Her past medical and social history was unremarkable. She had no previous history of any viral or bacterial disease and no history of oncological disorders. Autopsy revealed multiple grayish-white nodular lesions in the pleura and epicardial fat and areas resembling fibrosis on the cut surface of the anterior and posterior wall of the left ventricle and interventricular septum. Histological examination of the lungs and heart revealed multiple well-formed noncaseating epithelioid cell granulomas with multinucleated giant cells. Death was attributed to myocardial ischemia due to vasculitis of intramural coronary artery branches associated with sarcoidosis. Sarcoidosis is a multisystemic disease of unknown etiology characterized by the formation of noncaseating epithelioid cell granulomas in the affected organs and tissues. The diagnosis of sarcoidosis in this case was established when other causes of granulomatous disease such as tuberculosis, berylliosis, hypersensitivity pneumonitis, and giant cell myocarditis had been reasonably excluded.

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“…Cardiac and neurologic involvement may cause morbidity and death [1, 2]. Löfgren syndrome, an acute presentation of sarcoidosis, is characterized by erythema nodosum, BHL, and polyarthralgia and is associated with spontaneous regression [3, 4]. Additionally, more than 50% of sarcoidosis patients will experience remission within 3 years after diagnosis, with over 66% of patients experiencing remission within 10 years [5, 6].…”

Section: Sarcoidosis: Overview and Need For Biomarkersmentioning

confidence: 99%