2013
DOI: 10.1016/j.aquatox.2013.10.021
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Locomotor behavior in zebrafish (Danio rerio) larvae exposed to perfluoroalkyl acids

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Cited by 85 publications
(49 citation statements)
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“…In the recent past, PFCAs have been ubiquitously detected and characterized as persistent, bioaccumulative, and toxic (PBT) pollutants21222324. Thus, increasing attention has been focused on understanding the behavior and fate of these analogues in multiple environmental matrices.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In the recent past, PFCAs have been ubiquitously detected and characterized as persistent, bioaccumulative, and toxic (PBT) pollutants21222324. Thus, increasing attention has been focused on understanding the behavior and fate of these analogues in multiple environmental matrices.…”
Section: Discussionmentioning
confidence: 99%
“…Several studies have shown that the thermolysis of PTFE fluoropolymer can produce a variety of perfluorinated compounds (PFCs), such as environmentally persistent perfluorocarboxylic acids (PFCAs)1920. These chemicals have increasingly attracted worldwide concerns due to their persistence in environmental matrices and potential negative impacts on living organisms21222324. Given the PTFE backbone in Nafion, it is reasonable to assume that some similar products can also be generated when it is thermally treated.…”
mentioning
confidence: 99%
“…Adult behavioral and cognitive disturbances were reported A C C E P T E D M A N U S C R I P T ACCEPTED MANUSCRIPT 17 after exposure of rodent pups to PFAAs, usually at high doses [241][242][243]. Abnormal motor neuron development and locomotion were seen in zebrafish larvae exposed to PFAAs [256,257]. Very little information is found about other PFASs than PFOA and PFOS, and other species, in particular wildlife.…”
Section: Animals Experience a Range Of Adverse Effects Usually At Himentioning
confidence: 94%
“…For example, PFOS concentration in some biological species in Baiyangdian Lake achieved 2.07-16.84 ng/g dry weight [13]. Previous studies have shown that exposure to waterborne PFOS can elicit toxic responses like development toxicity, hepatotoxicity, immune toxicity, neurotoxicity and endocrine disrupting effects in aquatic organisms [14][15][16]. A recent research work has revealed that PFOS exposure can lead to developmental toxicity and cell apoptosis in planarian Dugesia japonica [16].…”
Section: Introductionmentioning
confidence: 95%